Table 1 Characteristics of 7 eligible studies
Author (year) [Ref] | Country | Diagnosis | Age of patients (Years) | Sample size (EIN/EN) | Elements of EIN | Nature of EN | EIN initiation time | Total during time of nutrition support (days) | Mode of enteral feeding | Reported Outcomes |
|---|---|---|---|---|---|---|---|---|---|---|
Liu et al. (2012) [18] | China | Advanced gastric cancer | 57.3 ± 7.1 (EIN) 58.4 ± 6.3 (EN) | 28/24 | Arg and Gln | Standard EN | Post-operation | 7 | Nasoenteral | Total protein, albumin, proalbumin, transrerrin, CD4+, CD8+, IgM, IgG, LHS, postoperative complications, incision infection, pulmonary infection |
Okamoto et al. (2009) [20] | Japan | Gastric carcinoma | 66.9 ± 11.5 (EIN) 70.9 ± 13.2(EN) | 30/30 | Arg, ω-3-FAs and RNA | Standard EN | Pre--operation | 7 | Oral | CD4+, CD8+, CD4+/CD8+, SIRS, lymphocyte, LHS, postoperative complications, operation time, intraoperative blood loss |
Chen et al. (2005) [10] | China | Gastric carcinoma | unclear | 20/20 | Arg, Gln, and ω-3-FAs | Standard EN | Post-operation | 7 | Nasoenteral | Proalbumin, albumin, transrerrin, CD4+, CD8+, CD4+/CD8+, IgM, IgG |
Mochiki et al. (2011) [16] | Japan | Gastric cancer | 65 ± 2.6 (EIN) 59 ± 2.1 (EN) | 15/16 | Gln | Oral placebo | Post-operation | unclear | Oral | Operation time, intraoperative blood loss |
Farreras et al. (2005) [19] | Spain | Gastric cancer | 66.7 ± 8.3 (EIN) 69.2 ± 13.8(EN) | 30/30 | Arg,Gln and ω-3-FAs | Standard EN | Post-operation | 7 | Oral | Total protein, proalbumin, albumin, lymphocyte, incision infection, pulmonary infection, postoperative complications, mortality |
Marano et al. (2013) [21] | Italy | Gastric adenocarcinoma | 66.6 (55-78) (EIN) 65.1 (49-83) (EN) | 54/55 | Arg,Gln, ω-3-FAs and RNA | Standard EN | Post-operation | 7 | Oral | Total protein, albumin, transrerrin, CD4+, CD8+, lymphocyte, LHS, SIRS, postoperative complications, operation time, incision infection, mortality, intraoperative blood loss |
Fujitani et al. (2012) [17] | Japan | Gastric adenocarcinoma | 64 (26-78) (EIN) 65(30-79) (EN) | 120/111 | Arg and RNA | Regular diet | Pre--operation | 5 | Oral | mortality, pulmonary infection, postoperative complications |