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Table 2 Univariate analysis and multivariate linear regression analysis of the variables associated with PHLF

From: Prediction of posthepatectomy liver failure using transient elastography in patients with hepatitis B related hepatocellular carcinoma

Variables Univariate analysis Multivariate analysis
PLF(+)(n = 37) PLF(−)(n = 210) p Exp(B) OR95%CI p
Age (years) 54.9 ± 10.9 53.0 ± 10.2 0.286    
Gender (Male /Female) 33/4 (89%/11%) 180/30 (86%/14%) 0.572    
BMI (kg /m2) 23.7 ± 3.1 23.3 ± 3.0 0.423    
White blood cell (109/l) 4.9 ± 1.5 5.3 ± 2.1 0.275    
Hemoglobin (g/l) 144.2 ± 12.3 143.8 ± 14.4 0.881    
Platelet Count (109/l) 139.0 ± 79.9 155.3 ± 56.9 0.037    
Total bilirubin (umol/l) 19.1 ± 8.8 15.4 ± 12.2 0.079    
Albumin (g/l) 41.0 ± 3.6 41.9 ± 3.2 0.123    
Prealbumin (mg/l) 218.2 ± 67.9 242.2 ± 61.0 0.032    
Alanine transaminase (u/l) 43.2 ± 31.3 38.5 ± 34.7 0.449    
Aspartate aminotransferase (u/l) 41.2 ± 23 36.1 ± 32.4 0.366    
Gamma-glutamyl transpeptidase (u/l) 104.8 ± 148.6 68.6 ± 69.2 0.027    
Alkaline phosphatase (u/l) 100.0 ± 47.4 83.2 ± 23.3 0.173    
PT(s) 12.1 ± 1.2 11.6 ± 0.8 0.005    
INR 1.0 ± 0.1 1.0 ± 0.1 0.005 1.065 1.014–1.119 0.013
APTT(s) 28.9 ± 5.9 27.1 ± 5.2 0.067    
LSM(kpa) 21.4 ± 6.3 12.7 ± 5.7 <0.001 1.211 1.134–1.293 <0.001
Intraoperative blood infusion (yes /no) 7/30 (18.9%/81.1%) 12/198 (5.7%/94.3%) 0.005    
Portal vein occlusion (yes/no) 24/13 (64.9%/35.1%) 160/50 (76.2%/23.8%) 0.145    
Number of tumors (Single/multiple) 32/5 (86.5%/13.5%) 185/25 (88.1%/11.9%) 0.782    
Tumor capsule (yes/no) 24/13 (64.9%/35.1%) 150/60 (71.4%/28.6%) 0.420    
HBV DNA levels (>1.0E + 04iu/ml/<1.0E + 04iu/ml) 13/24 (35.1%/64.9%) 60/150 (28.6%/71.4%) 0.422    
Cirrhosis (yes/no) 22/15 (59.5%/40.5%) 54/156 (27.7%/74.3%) <0. 001    
Esophageal varices (yes/no) 7/30 (18.9%/81.1%) 11/199 (5.2%/94.8%) 0.003    
Major hepatectomy 8 (22%) 32 (15%) 0.331    
Median main tumor size (cm) 5.6 ± 4.0 4.9 ± 3 0.687    
Tumor location (right lobe/left lobe/both) 29/6/2 (78.4%/16.2%/5.4%) 129/73/8 (61.4%/34.8%/3.8%) 0.082