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Table 2 Univariate analysis and multivariate linear regression analysis of the variables associated with PHLF

From: Prediction of posthepatectomy liver failure using transient elastography in patients with hepatitis B related hepatocellular carcinoma

Variables

Univariate analysis

Multivariate analysis

PLF(+)(n = 37)

PLF(−)(n = 210)

p

Exp(B)

OR95%CI

p

Age (years)

54.9 ± 10.9

53.0 ± 10.2

0.286

   

Gender (Male /Female)

33/4 (89%/11%)

180/30 (86%/14%)

0.572

   

BMI (kg /m2)

23.7 ± 3.1

23.3 ± 3.0

0.423

   

White blood cell (109/l)

4.9 ± 1.5

5.3 ± 2.1

0.275

   

Hemoglobin (g/l)

144.2 ± 12.3

143.8 ± 14.4

0.881

   

Platelet Count (109/l)

139.0 ± 79.9

155.3 ± 56.9

0.037

   

Total bilirubin (umol/l)

19.1 ± 8.8

15.4 ± 12.2

0.079

   

Albumin (g/l)

41.0 ± 3.6

41.9 ± 3.2

0.123

   

Prealbumin (mg/l)

218.2 ± 67.9

242.2 ± 61.0

0.032

   

Alanine transaminase (u/l)

43.2 ± 31.3

38.5 ± 34.7

0.449

   

Aspartate aminotransferase (u/l)

41.2 ± 23

36.1 ± 32.4

0.366

   

Gamma-glutamyl transpeptidase (u/l)

104.8 ± 148.6

68.6 ± 69.2

0.027

   

Alkaline phosphatase (u/l)

100.0 ± 47.4

83.2 ± 23.3

0.173

   

PT(s)

12.1 ± 1.2

11.6 ± 0.8

0.005

   

INR

1.0 ± 0.1

1.0 ± 0.1

0.005

1.065

1.014–1.119

0.013

APTT(s)

28.9 ± 5.9

27.1 ± 5.2

0.067

   

LSM(kpa)

21.4 ± 6.3

12.7 ± 5.7

<0.001

1.211

1.134–1.293

<0.001

Intraoperative blood infusion (yes /no)

7/30 (18.9%/81.1%)

12/198 (5.7%/94.3%)

0.005

   

Portal vein occlusion (yes/no)

24/13 (64.9%/35.1%)

160/50 (76.2%/23.8%)

0.145

   

Number of tumors (Single/multiple)

32/5 (86.5%/13.5%)

185/25 (88.1%/11.9%)

0.782

   

Tumor capsule (yes/no)

24/13 (64.9%/35.1%)

150/60 (71.4%/28.6%)

0.420

   

HBV DNA levels (>1.0E + 04iu/ml/<1.0E + 04iu/ml)

13/24 (35.1%/64.9%)

60/150 (28.6%/71.4%)

0.422

   

Cirrhosis (yes/no)

22/15 (59.5%/40.5%)

54/156 (27.7%/74.3%)

<0. 001

   

Esophageal varices (yes/no)

7/30 (18.9%/81.1%)

11/199 (5.2%/94.8%)

0.003

   

Major hepatectomy

8 (22%)

32 (15%)

0.331

   

Median main tumor size (cm)

5.6 ± 4.0

4.9 ± 3

0.687

   

Tumor location (right lobe/left lobe/both)

29/6/2 (78.4%/16.2%/5.4%)

129/73/8 (61.4%/34.8%/3.8%)

0.082