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Table 1 Baseline Characteristics of CHC, GT1 Patients

From: CCL4 is the only predictor for non-responder in GT-1 CHC patients with favorable IL28B genotype when treated with PegIFN/RBV

Variables Overall NR (22)a non-NR (38)a P value
Age (years) 58.23 ± 9.19 55.6 ± 9.2 59.8 ± 9.0 0.090
Male (%) 55.0 50.0 57.9 0.599
BMI (Kg/m2) 25.44 ± 3.22 25.5 ± 3.7 25.4 ± 2.9 0.865
AST (U/L) 80.85 ± 40.27 91 ± 48 75 ± 34 0.118
ALT (U/L) 105.63 ± 59.86 108 ± 53 104 ± 64 0.797
HCV RNA (log10 IU/ml) 3.38(5.17)b 2.48(4.74)b 3.72(5.66)b 0.591
Diabetes Mellitus (%) 25.0 13.6 31.6 0.215
IL28B (CC %) 75.0 50.0 89.5 0.001
Liver cirrhosis (%) 28.3 45.5 18.4 0.038
  1. anumber of patients shown in parentheses
  2. bmedian (IQR) shown in parentheses
  3. Data are shown as mean ± standard deviation. Statistic analysis was done by Mann-Whitney test for comparison. Significant P values are shown in bold. AST, aspartate aminotransferase; ALT, alanine aminotransferase; HCV, hepatitis C virus; IL28B, Interleukin-28B