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Table 4 Diagnostic efficiency of radiological findings in CT and MRI and their logical sum

From: Efficacy comparison of multi-phase CT and hepatotropic contrast-enhanced MRI in the differential diagnosis of focal nodular hyperplasia: a prospective cohort study

  sensitivity specificity PPV NPV accuracy
CT isodense focus in NECT 0.93 0.74 0.36 0.99 0.76
homogeneous enhancement in HAP 0.84 0.77 0.36 0.97 0.78
isodense to liver enhancement in PVP 0.80 0.80 0.38 0.96 0.80
isodense to liver enhancement in EP 1.00 0.43 0.22 1.00 0.51
central scar 0.53 0.99 0.89 0.93 0.93
homogeneous enhancement in HAP and central scar 0.47 0.99 0.88 0.93 0.93
homogeneous enhancement in HAP and isodense to liver enhancement in PVP 0.71 0.95 0.67 0.96 0.92
homogeneous enhancement in HAP and isodense to liver enhancement in PVP no cirrhosis 0.71 0.97 0.76 0.96 0.94
homogeneous enhancement in HAP and isodense to liver enhancement in PVP no neoplastic disease in anamnesis 0.55 0.83 0.29 0.94 0.80
MRI isointense focus in T1 W 0.44 0.84 0.27 0.92 0.79
isointense focus in T2 W 0.84 0.85 0.44 0.98 0.85
central scar 0.73 0.99 0.87 0.96 0.96
homogeneous enhancement in HAP 0.89 0.75 0.32 0.98 0.77
isointense to liver enhancement in PVP 0.82 0.79 0.34 0.97 0.79
non-hypointense focus in HBP 1.00 0.94 0.68 1.00 0.94
homogeneous enhancement in HAP non-hypointense focus in HBP 0.89 0.97 0.82 0.98 0.96
homogeneous enhancement in HAP non-hypointense focus in HBP central scar 0.64 1.00 1.00 0.95 0.96
non-hypointense focus in HBP no neoplastic disease in anamnesis 0.55 0.93 0.56 0.92 0.87
non-hypointense focus in HBP no cirrhosis 1.00 0.99 0.94 1.00 0.99
homogeneous enhancement in HAP no cirrhosis 0.89 0.83 0.39 0.99 0.84
homogeneous enhancement in HAP non-hypointense focus in HBP no cirrhosis 0.89 1.00 1.00 0.99 0.99
  1. The logic sum of radiological findings with the highest diagnostic efficiency in italic. HAP Hepatic arterial phase, HBP Hepatobiliary phase, NPV Negative predictive value, NECT Non-enhanced computed tomography, PVP Portal venous phase, PPV Positive predictive value, T1 W T1-weighted images, T2 W T2-weighted images