Outcome | Open necrosectomy after PCD(n = 12) | Percutaneous debridement after PCD (n = 15) | Risk ratio (95% CI) | P value |
---|---|---|---|---|
Primary composite end point: major complications or death - no. (%)a | 11 (92%) | 8 (53%) | 1.71 (1.04–2.84) | 0.04 |
Secondary end points | ||||
Major complication - no. (%) | ||||
New-onset organ failure | 7 (58%) | 2 (13%) | 4.38 (1.11–17.32) | 0.04 |
Multiple-organ failure | 3 (25%) | 0 | 0.08 | |
Intestinal fistula | 6 (50%) | 7 (47%) | 1.07 (0.49–2.34) | 0.86 |
Intra-abdominal bleeding | 3 (25%) | 1 (7%) | 3.75 (0.45–31.62) | 0.29 |
Stress ulcer with bleeding | 2 (17%) | 0 | 0.19 | |
Other outcome | ||||
Intestinal obstruction | 2 (17%) | 0 | 0.19 | |
Cerebral infarction | 1 (8%) | 0 | 0.44 | |
Arrhythmia | 0 | 1 (7%) | 0.27 | |
Death - no. (%) | 2 (17%) | 0 | 0.19 | |
Postoperative ICU admission time | 0.02 | |||
Median | 17 | 0 | ||
IQR | 7–35 | 0–9 | ||
Days in hospital | 0.25 | |||
Median | 62 | 52 | ||
IQR | 40–73 | 41–60 |