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Table 4 Cox-Regression Analysis of Predictors for 60-day Mortality (Multivariate Analysis)

From: Risk factors for mortality among patients admitted with upper gastrointestinal bleeding at a tertiary hospital: a prospective cohort study

Predictor

Hazard Ratio (95% CI)

P value

Renal Insufficiency

1.38 (0.54–3.51)

0.504

Encephalopathy

1.19 (0.46–3.06)

0.723

HIV

0.58 (0.16–2.07)

0.402

Diabetes Mellitus

2.14 (0.54–8.50)

0.279

Malignancy

0.58 (0.21–1.64)

0.303

White Blood Cell Count >11 k/μl

2.45 (1.23–4.89)

0.011

Serum Creatinine >115 μmol/L

1.55 (0.57–4.23)

0.896

Serum BUN >7.4 g/dL

1.46 (0.55–3.85)

0.445

Serum ALT >55 U/L

4.22 (1.31–13.57)

0.016

Serum AST > 34 U/L

1.11 (0.39–3.17)

0.843

Serum Total Bilirubin >20.5 μmol/L

5.79 (1.58–21.25)

0.008

Prothrombin Time > 12.1 s

0.33 (0.01–21.14)

0.598

INR > 1.13

8.57 (0.14–536.04)

0.309

Endoscopy Not Done

4.40 (2.11–9.17)

<0.001

  1. Multivariate analysis to identify independent predictors of 60-day mortality was done using Cox-Regression analysis. Factors that were shown to be significantly associated with a higher risk of 60-day mortality by bivariate analysis were included in the regression model. Multivariate analysis showed that a higher WBC count of >11 k/μl, a high serum ALT >55 U/L, a high serum total bilirubin >20.5 μmol/L were independently associated with an increased risk of mortality. Patients who did not undergo endoscopy had a 4.4 times higher rate of death within 60 days of admission (Table 4)
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BMC Gastroenterology

ISSN: 1471-230X

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