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Table 3 Subgroup analysis for studies of gastric cancer incidence in patients with gastric atrophy or intestinal metaplasia

From: Adenocarcinoma risk in gastric atrophy and intestinal metaplasia: a systematic review

Variable Gastric atrophy Intestinal metaplasia
Number of studies (references) I 2 (%) Number of studies (references) I 2 (%)
Age (mean, years) ≥55 4([11, 25, 35, 36]) 96 7([12, 18, 19, 26, 36, 39, 40]) 94
<55 3([10, 17, 38]) 13 2([27, 38]) 90
Male (% study population) ≥50 3([8, 25, 36]) 98 6([12, 26, 27, 36, 38, 40]) 95
<50 4([10, 11, 17, 38]) 0 2([18, 39]) 92
Country/Region Asia 3([8, 10, 25]) 94 1([27]) NA*
Europe 5([11, 17, 35, 36, 38]) 82 4([12, 36, 38, 40]) 89
U.S.A. 0 NA* 4([18, 19, 26, 39]) 96
Study Quality (Newcastle-Ottawa Scale score) High (5–6) 4([11, 25, 36, 38]) 95 5([18, 27, 36, 38, 39]) 90
Moderate (3–4) 4([8, 10, 17, 35]) 72 4([12, 19, 26, 40]) 88
  1. *NA Not applicable