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Fig. 1 | BMC Gastroenterology

Fig. 1

From: Gut microbiota-mediated generation of saturated fatty acids elicits inflammation in the liver in murine high-fat diet-induced steatohepatitis

Fig. 1

The gut microbiota contributes to the development of NASH induced by STHD-01. a Experimental protocol. CAZ; Ceftazidime. MNZ; Metronidazole. b Total calorie intake, total water intake, liver/body weight ratios, body weight, and plasma triiodothyronine (T3) and thyroxin (T4) were measured at 17 weeks. c Representative histological image of the liver. d Plasma aspartate aminotransferase (AST) and alanine aminotransferase (ALT), liver triglyceride (TG), and transcription of TNF-α, IL-1β, α-SMA, and Col1α1 in the liver tissue were measured. b, d Data are presented as mean ± SEM (N = 7). *P < 0.05, ***P < 0.001 by the Tukey’s test. The cut-off value of T3 was 0.16 ng/ml and T4 was 0.5 μg/dl. The cut-off value of AST and ALT were 9 IU/dl. The cut-off value of TG was 0.19 mg/g liver

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