The red distribution width and the platelet distribution width as prognostic predictors in gastric cancer

BMC Gastroenterology

Table 4 Univariate and multivariate survival analysis results of 164 patients with GC at early stage

Variables	Univariate^a (OS)		Univariate^a (DFS)		Multivariate^b(DFS)
Variables	HR(95% CI)	P value	HR(95% CI)	P value	HR(95% CI)	P value
RDW(<12.85/≥12.85)	57.198(0.042–7.805E4)	0.272	5.776(1.292–25.821)	0.022	5.346(1.195–23.917)	0.028
PDW(<11.95/≥11.95)	0.265 (0.029–2.387)	0.236	0.158(0.035–0.707)	0.016	0.170(0.038–0.761)	0.020
Gender(Male/Female)	1.526 (0.158–14.733)	0.715	2.983(0.973–9.150)	0.056
Age(<60/≥60)	2.264 (0.242–21.168)	0.474	1.145(0.378–3.470)	0.811
Tumor diameter(≤4/>4)	0.046 (0.000–1.144E7)	0.754	2.507(0.318–19.758)	0.383
Differentiation (Well/Moderate/ Poor)	2.384 (0.487–11.664)	0.284	0.717(0.334–1.540)	0.394
Lymph node metastasis (N0/N1 + N2 + N3)	1.460 (0.201–10.620)	0.708	1.706(0.513–5.671)	0.383
Distance metastasis (M0/M1)	0.047(0.000–1.212E9)	0.803	0.047(0.000–1.401E4)	0.634
pStage(I + II/III + IV)	2.243 (0.250–20.161)	0.471	1.478(0.330–6.615)	0.609
CEA(≤5/>5)	0.045 (0.000–2.044E14)	0.602	0.046(0.000–3.688E4)	0.657
CA125(≤35/>35)	1.000(0.000–2584.626)	1.000	0.046(0.000–4.070E7)	0.770
CA199(≤39/>39)	0.039 (0.000–5.365E7)	0.762	0.042(0.000–1.509E4)	0.627

Abbreviations: OS overall survival, DFS disease-free survival, HR hazard ratio, CI confidence interval, RDW red blood cell distribution width, CEA carcinoembryonic antigen, CA125 carbohydrate antigen 125, CA199 carbohydrate antigen 199
^aPerformed using the Kaplan–Meier analysis model and the log-rank test; values of P < 0.05 in the univariate analysis were entered into a multivariate analysis
^bperformed using Cox proportional hazards models with the forward likelihood method

ISSN: 1471-230X