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Table 3 Univariate and multivariate survival analysis results of 227 patients with GC

From: The red distribution width and the platelet distribution width as prognostic predictors in gastric cancer

Clinicopathological feature Univariatea(OS) Multivariateb(OS) Univariatea(DFS) Multivariateb(DFS)
HR (95% CI) P value HR(95% CI) P value HR (95% CI) P value HR(95% CI) P value
RDW(<13/≥13) 1.801 (0.985–3.291) 0.056    1.807 (1.015–3.217) 0.044   
PDW(<11.5/≥11.5) 0.701 (0.385–1.275) 0.244    0.754 (0.425–1.337) 0.333   
Gender(Male/Female) 0.764 (0.355–1.648) 0.493    0.908 (0.452–1.827) 0.787   
Age(<60/≥60) 1.541 (0.844–2.814) 0.160    1.535 (0.863–2.730) 0.044   
Tumor diameter(≤4/>4) 2.890 (1.553–5.375) 0.001    2.633 (1.465–4.731) 0.001   
Differentiation (Well/Moderate/ Poor) 1.968 (1.027–3.772) 0.041    1.650 (0.926–2.941) 0.089   
Depth of tumor (T1 + T2/T3 + T4) 2.169 (1.613–2.916) < 0.001 1.722(1.170–2.535) 0.006 2.097 (1.569–2.802) < 0.001 1.655(1.130–2.422) 0.010
Lymph node metastasis (N0/N1 + N2 + N3) 5.548 (2.335–13.181) < 0.001    4.548 (2.118–9.763) < 0.001   
Distance metastasis (M0/M1) 2.403 (1.112–5.193) 0.026    2.137 (0.996–4.584) 0.051   
pStage(I + II/III + IV) 7.841 (3.075–19.994) < 0.001 4.311(1.591–11.682) 0.004 6.179 (2.755–13.858) < 0.001 3.517(1.470–8.413) 0.005
CEA(≤5/>5) 1.240 (0.552–2.788) 0.602    1.116 (0.500–2.492) 0.789   
CA125(≤35/>35) 2.606 (0.353–19.240) 0.348    2.606 (0.353–19.240) 0.348   
CA199(≤39/>39) 2.405 (1.173–4.930) 0.017    2.478 (1.249–4.917) 0.009   
  1. Abbreviations: OS overall survival, DFS disease-free survival, HR hazard ratio, CI confidence interval, RDW red blood cell distribution width, CEA carcinoembryonic antigen, CA125 carbohydrate antigen 125, CA199 carbohydrate antigen 199
  2. aPerformed using the Kaplan–Meier analysis model and the log-rank test; values of P < 0.05 in the univariate analysis were entered into a multivariate analysis
  3. bperformed using Cox proportional hazards models with the forward likelihood method