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Table 3 Specific Symptom scores of GIS© at baseline and after 6 weeks of treatment

From: A non-interventional, observational study of a fixed combination of pepsin and amino acid hydrochloride in patients with functional dyspepsia

Symptom

Score at baseline [Mean± SD (N)]

Score at 6 weeks [Mean± SD (N)]

P: Difference to baseline score

Epigastric pain/ upper abdominal pain

1.65 ± 1,04 (94)

1.12 ± 0,97 (73)

< 0.0001

Abdominal cramps

1.23 ± 1.18 (94)

0.74 ± 0.89 (72)

0.003

Bloating

2.12 ± 1.08 (94)

1.32 ± 1.08 (73)

< 0.0001

Early satiety

1.06 ± 1.00 (94)

0.81 ± 0.90 (72)

0.006

Loss of appetite

0.74 ± 1.01 (93)

0.44 ± 0.83 (73)

0.042

Sickness

0.98 ± 1.10 (94)

0.72 ± 0.95 (73)

0.017

Nausea

0.27 ± 0.74 (94)

0.15 ± 0.57 (73)

0.35

Vomiting

0.22 ± 0.72 (94)

0.10 ± 0.48 (73)

0.51

Retrosternal discomfort

1.40 ± 1.00 (94)

0.95 ± 0.88 (73)

0.019

Acidic eructation/ Heartburn

1.80 ± 1.12 (94)

1.20 ± 1.03 (73)

< 0.0001