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Table 2 Twenty-four-hour ambulatory multichannel pH-impedance measurement results and BEWE scores at baseline and at follow-up off-PPI in patients with progression or no progression of dental erosion after a median of 1 year treatment with esomeprazole 20 mg twice-daily. Means and 95% confidence intervals are shown

From: Longitudinal study of gastroesophageal reflux and erosive tooth wear

  At baseline At follow-up
  All patients N = 72 All patients N = 72 No erosion progression N = 53 Erosion progression N = 19
% time with pH < 4a 16.5 (12.6–20.4) 11.7 (5.7–17.7) 10.2 (6.7–13.7) 16.9 (6.4–27.4)
% time with pH < 5.5a 43.5 (33.3–53.7) 40.2 (31.1–49.3) 40.5 (26.6–54.4) 37.7 (26.6–48.8)
DeMeester scorea 56.4 (43.2–69.6) 46.3 (34.3–54.3) 41.7 (31.8–51.6) 69.1 (40.1–98.1)
Number of all reflux episodes (pH < 7)b 85 (64–106) 52 (41–63)* 53 (46–61)** 52 (33–71)
Number of acidic reflux episodes (pH < 4)b 54 (41–67) 41 (31–50) 43 (37–49) 33 (24–42)
Number of weakly acidic reflux episodes (pH > 4–pH < 7)b 31 (24–38) 12 (8–18)** 10 (8–12)** 19 (10–28)
% proximal reflux (15 cm above lower oesophageal sphincter)a 26 (20–32) 23 (17–29) 23 (19–27) 21 (15–27)
BEWE scoresb 12 (11–16) 13 (12–15) 12 (11–13) 14 (13–16)***
  1. BEWE Basic erosive wear examination (9–13 medium, >13 extensive erosive disease) [7]
  2. ameans (95% confidence intervals)
  3. bmedian (interquartile range)
  4. *p < 0.05 versus baseline **p < 0.01 versus baseline ***p < 0.01 group with erosion progression vs group without erosion progression