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Table 2 The results of 24-h MII-pH monitoring and esophageal HRM in 2 cohorts

From: The diagnostic value of pepsin detection in saliva for gastro-esophageal reflux disease: a preliminary study from China

Parameters

Non-GERD (n = 128)

GERD (n = 122)

P

24-h MII-pH monitoring

   

 Demeester score, median (IQR)

11.2 (8.8–13)

26.3 (14.0–51.7)

<0.001

 AET (%), median (IQR)

3.1 (2.1–3.7)

8.9 (4–12.1)

<0.001

 BET (%), median (IQR)

1.05 (0.8–1.2)

2 (0.4–5.5)

0.006

 Number of all reflux episodes, median (IQR)

63 (51.3–69)

75 (55.8–117.3)

<0.001

HRM

 Resting LES pressure (mmHg), median ( IQR)

12.4 (7.3–18)

8.4 (4.4–12)

<0.001

 Resting UES pressure (mmHg), median (IQR)

57.2 (34.2–84.9)

58.4 (39.6–80.7)

0.605

HH# (%)

24.2

73.0

<0.001

  1. 24-h MII-pH 24-h multichannel intraluminal impedance pH, IQR interquartile rang, GERD gastro-esophageal reflux disease, AET acid exposure time, BET bolus exposure time, HRM high resolution manometry, LES lower esophageal sphincter, UES upper esophageal sphincter, HH hiatal hernia
  2. #HH was detected by endoscopy combined with HRM