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Table 1 General characteristics of the eligible publications in this study

From: p53 expression in patients with ulcerative colitis - associated with dysplasia and carcinoma: a systematic meta-analysis

First author

Country

Ethnicity

Age

Cut-off (IHC)

Location

Normal

UC

UC with dysplasia

UC with cancer

NOS

N (E%)

N (E%)

N (E%)

N (E%)

Taylor 1993 [29]

UK

Caucasians

NA

NA

Nucleus

 

20 (0)

20 (30)

21 (52.4)

9

Harpaz 1994 [28]

USA

Caucasians

NA

10%

Nucleus

  

40 (62.5)

56 (60.7)

7

Klump 1997 [15]

Germany

Caucasians

NA

0%

Nucleus

 

68 (2.9)

27 (63)

5 (100)

8

Fogt 1998 [27]

USA

Caucasians

NA

0%

Nucleus

  

10 (90)

8 (87.5)

7

Sato 1999 [26]

Japan

Asians

NA

NA

Nucleus

35 (14.3)

105 (41)

55 (67.3)

11 (90.9)

6

Hirota 2000 [25]

Japan

Asians

NA

Focal or diffuse

Nucleus

  

40 (60)

13 (92.3)

6

Ishitsuka 2001 [24]

Japan

Asians

NA

Local or diffuse

Nucleus

 

23 (0)

13 (61.5)

4 (75)

6

Brüwer 2002 [23]

Germany

Caucasians

NA

0%

Nucleus

10 (0)

15 (6.7)

16 (37.5)

14 (57.1)

9

Li 2004 [17]

China

Asians

44

10%

Nucleus

25 (0)

5 (0)

14 (21.4)

2 (50)

7

Yoshida 2004 [22]

Japan

Asians

NA

Scattered

Nucleus

7 (28.6)

19 (26.3)

46 (63)

7 (57.1)

7

Wang 2005 [30]

China

Asians

44

1%

Nucleus

 

25 (4)

7 (42.9)

8 (50)

8

Wang 2008 [31]

China

Asians

32

5%

Nucleus

10 (10)

20 (15)

  

6

Alkim 2009 [37]

Turkey

Caucasians

46

0%

Nucleus

10 (40)

26 (88.5)

  

7

Kawamata 2011 [14]

Japan

Asians

28–60

NA

Nucleus

12 (0)

8 (12.5)

8 (62.5)

8 (75)

8

Tanaka 2011 [36]

Japan

Asians

49.5

Focal

Nucleus

 

28 (0)

81 (59.3)

10 (90)

6

Gushima 2011 [35]

Japan

Asians

49

10%

Nucleus

  

11 (72.7)

14 (21.4)

8

Scarpa 2013 [34]

Italy

Caucasians

51

NA

Nucleus

11 (9.1)

19 (5.3)

10 (20)

7 (57.1)

8

Shigaki 2013 [32]

Japan

Asians

26–80

5%

Nucleus

  

58 (46.6)

27 (59.3)

7

Wohl 2013 [33]

Czech Republic

Caucasians

NA

33%

Nucleus

10 (0)

16 (6.3)

  

7

  1. NA not applicable, UC ulcerative colitis, IHC immunohistochemistry, N study population, NOS Newcastle-Ottawa Scale, E expression