Skip to main content

Advertisement

Table 1 General characteristics of the eligible publications in this study

From: p53 expression in patients with ulcerative colitis - associated with dysplasia and carcinoma: a systematic meta-analysis

First author Country Ethnicity Age Cut-off (IHC) Location Normal UC UC with dysplasia UC with cancer NOS
N (E%) N (E%) N (E%) N (E%)
Taylor 1993 [29] UK Caucasians NA NA Nucleus   20 (0) 20 (30) 21 (52.4) 9
Harpaz 1994 [28] USA Caucasians NA 10% Nucleus    40 (62.5) 56 (60.7) 7
Klump 1997 [15] Germany Caucasians NA 0% Nucleus   68 (2.9) 27 (63) 5 (100) 8
Fogt 1998 [27] USA Caucasians NA 0% Nucleus    10 (90) 8 (87.5) 7
Sato 1999 [26] Japan Asians NA NA Nucleus 35 (14.3) 105 (41) 55 (67.3) 11 (90.9) 6
Hirota 2000 [25] Japan Asians NA Focal or diffuse Nucleus    40 (60) 13 (92.3) 6
Ishitsuka 2001 [24] Japan Asians NA Local or diffuse Nucleus   23 (0) 13 (61.5) 4 (75) 6
Brüwer 2002 [23] Germany Caucasians NA 0% Nucleus 10 (0) 15 (6.7) 16 (37.5) 14 (57.1) 9
Li 2004 [17] China Asians 44 10% Nucleus 25 (0) 5 (0) 14 (21.4) 2 (50) 7
Yoshida 2004 [22] Japan Asians NA Scattered Nucleus 7 (28.6) 19 (26.3) 46 (63) 7 (57.1) 7
Wang 2005 [30] China Asians 44 1% Nucleus   25 (4) 7 (42.9) 8 (50) 8
Wang 2008 [31] China Asians 32 5% Nucleus 10 (10) 20 (15)    6
Alkim 2009 [37] Turkey Caucasians 46 0% Nucleus 10 (40) 26 (88.5)    7
Kawamata 2011 [14] Japan Asians 28–60 NA Nucleus 12 (0) 8 (12.5) 8 (62.5) 8 (75) 8
Tanaka 2011 [36] Japan Asians 49.5 Focal Nucleus   28 (0) 81 (59.3) 10 (90) 6
Gushima 2011 [35] Japan Asians 49 10% Nucleus    11 (72.7) 14 (21.4) 8
Scarpa 2013 [34] Italy Caucasians 51 NA Nucleus 11 (9.1) 19 (5.3) 10 (20) 7 (57.1) 8
Shigaki 2013 [32] Japan Asians 26–80 5% Nucleus    58 (46.6) 27 (59.3) 7
Wohl 2013 [33] Czech Republic Caucasians NA 33% Nucleus 10 (0) 16 (6.3)    7
  1. NA not applicable, UC ulcerative colitis, IHC immunohistochemistry, N study population, NOS Newcastle-Ottawa Scale, E expression