|  | Stent dysfunction (n = 44) | univariate | multivariate | |||||
---|---|---|---|---|---|---|---|---|---|
n | Â | HR | 95% CI | P value | HR | 95% CI | P value | ||
Type of stent | Uncovered | 44 | 20 | 1 | |||||
Partially | 28 | 8 | 0.33 | 0.14–0.79 | 0.012* | 0.30 | 0.11–0.77 | 0.013* | |
Fully | 29 | 16 | 0.96 | 0.49–1.85 | 0.892 | 0.92 | 0.43–1.95 | 0.822 | |
Age | <75 | 48 | 20 | 1 | |||||
≥75 | 53 | 24 | 1.25 | 0.68–2.30 | 0.464 | ||||
Sex | male | 41 | 23 | 1 | |||||
female | 60 | 21 | 1.54 | 0.84–2.80 | 0.162 | 1.50 | 0.75–3.03 | 0.256 | |
Performance status | 0–2 | 93 | 41 | 1 | |||||
3,4 | 8 | 3 | 3.14 | 0.93–10.60 | 0.066 | 4.91 | 1.13–21.40 | 0.034* | |
Primary malignancy | others | 21 | 3 | 1 | |||||
pancreatic | 80 | 41 | 2.89 | 0.89–9.35 | 0.077 | 3.76 | 1.10–12.87 | 0.035* | |
location of stricture | lower | 76 | 34 | 1 | |||||
middle | 25 | 10 | 0.64 | 0.31–1.35 | 0.241 | ||||
Length of stricture | ≤20 mm | 53 | 20 | 1 | |||||
>20 mm | 48 | 24 | 1.61 | 0.88–2.95 | 0.120 | 1.33 | 0.69–2.54 | 0.395 | |
Stent length | ≤6 cm | 88 | 39 | 1 | |||||
8 cm | 13 | 5 | 2.24 | 0.87–5.77 | 0.095 | 2.16 | 0.73–6.38 | 0.165 | |
Length of a portion of the stent over the stricture | <30Â mm | 49 | 23 | 1 | |||||
≥30 mm | 52 | 21 | 1.09 | 0.59–1.99 | 0.787 | ||||
Prior transpapillary Drainage | No | 41 | 15 | 1 | |||||
Yes | 60 | 29 | 0.72 | 0.38–1.36 | 0.310 | ||||
History of cholecystectomy | No | 94 | 43 | 1 | |||||
Yes | 7 | 1 | 0.62 | 0.08–4.53 | 0.638 | ||||
EST | No | 14 | 7 | 1 | |||||
Yes | 87 | 37 | 0.72 | 0.30–1.72 | 0.464 | ||||
duodenal invasion | absent | 67 | 22 | 1 | |||||
present | 34 | 22 | 1.68 | 0.92–3.06 | 0.091 | 1.62 | 0.81–3.25 | 0.172 | |
Duodenal stent | absent | 85 | 35 | 1 | |||||
Present | 16 | 9 | 1.29 | 0.60–2.79 | 0.518 | ||||
Chemotherapy | No | 30 | 9 | 1 | |||||
Yes | 71 | 35 | 0.55 | 0.26–1.17 | 0.120 | 0.47 | 0.19–1.15 | 0.098 |