Table 1 Baseline Characteristics of patients in relation to HBV DNA levels
From: Diminished accuracy of biomarkers of fibrosis in low replicative chronic hepatitis B
Parameters | HBV DNA < 20,000 IU/mL (n = 213) | HBV DNA > 20,000 IU/mL (n = 153) | P value |
|---|---|---|---|
Age (years) | 38.2 ± 11.7 | 39.1 ± 12.0 | 0.485 |
Male gender (%) | 156 (73.2) | 116 (75.8) | 0.578 |
BMI (Kg/m2) | 29.5 ± 10.4 | 26.9 ± 4.9 | 0.002 |
Diabetes mellitus (%) | 30 (14.1) | 20 (13.1) | 0.781 |
Hyperlipidemia (%) | 41 (19.2) | 31 (20.3) | 0.810 |
HBV DNA Log10 | 3.3 ± 0.7 | 6.1 ± 1.3 | < 0.0001 |
Platelets (109) | 255.3 ± 68.9 | 232.2 ± 61.8 | 0.001 |
Elevated AST (%) | 41 (20.0) | 80 (54.1) | < 0.0001 |
Normal ALT (%) | 118 (55.4) | 30 (19.6) | < 0.0001 |
Elevated ALT (%) | 95 (44.6) | 123 (80.4) | |
Fibrosis (F2–4, %) | 40 (18.8) | 73 (47.7) | < 0.0001 |