Table 2 Characteristics of ALT responders and non-responders
|  | ALT responders (n = 15) | ALT non-responders (n = 14) | P-value |
|---|---|---|---|
Age (year) | 50.7 ± 12.1 | 61.7 ± 12.4 | 0.011 |
Male/female (n) | 9 (6) | 5 (9) | 0.191 |
Dyslipidemia (%) | 12 (80.0) | 12 (85.7) | 0.68 |
Statin (%) | 4 (26.7) | 8 (57.1) | 0.10 |
Diabetes (%) | 5 (33.3) | 9 (64.3) | 0.10 |
BMI (kg/m2) | 26.5 ± 4.1 | 26.6 ± 3.8 | 0.47 |
FBS (mg/dL) | 115.7 ± 37.9 | 121.4 ± 31.2 | 0.33 |
IRI (μU/mL) | 23.5 ± 22.7 | 22.6 ± 38.0 | 0.47 |
HbA1c (%) | 5.94 ± 1.03 | 6.9 ± 1.2 | 0.019 |
HDL cholesterol (mg/dL) | 60.3 ± 18.6 | 49.7 ± 11.7 | 0.04 |
LDL cholesterol (mg/dL) | 124.5 ± 33.1 | 102.9 ± 18.6 | 0.021 |
Triglycerides (mg/dL) | 202.4 ± 164.1 | 187.6 ± 103.3 | 0.39 |
NEFA (μEq/L) | 720.2 ± 285.0 | 563.3 ± 143.0 | 0.055 |
AST (IU/L) | 46.3 ± 20.2 | 47.1 ± 14.1 | 0.45 |
ALT (IU/L) | 77.1 ± 38.6 | 60.1 ± 32.2 | 0.104 |
GGT (IU/L) | 81.9 ± 58.0 | 58.0 ± 26.6 | 0.085 |
Ferritin (ng/mL) | 260.2 ± 164.5 | 176.6 ± 126.1 | 0.07 |
Platelet count (×104 /μL) | 20.3 ± 4.6 | 21.3 ± 6.8 | 0.32 |
Type IV collagen 7 s | 4.61 ± 1.13 | 5.59 ± 2.51 | 0.09 |
Glutathione in protein fraction (μM) | 1.53 ± 0.92 | 1.27 ± 0.83 | 0.230 |
Glutathione in deprotenized fraction (μM) | 0.017 ± 0.020 | 0.036 ± 0.057 | 0.116 |
CAP (db/m) | 300.3 ± 41.1 | 290.4 ± 50.2 | 0.29 |
LSM (kPa) | 8.71 ± 4.63 | 11.36 ± 5.05 | 0.080 |