Fig. 2

Microscopic images of the esophagus. a, b Low power images of the esophageal wall. The epithelium has entirely sloughed off. A dense lichenoid lymphocytic infiltrate involves the lamina propria and muscularis mucosae. Esophageal glands in the submucosa are uninvolved. c Medium power image of the lichenoid infiltrate showing extension into the muscularis mucosae. The epithelium has entirely sloughed off. d, e Medium-high power images of the lymphoid infiltrate. The twisted appearance of many of the lymphocyte nuclei is typical of T-cells and does not imply atypia. f Medium-high power view of the lymphocytes showing uniformly strong positivity with the T-cell marker CD43