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Table 2 Densities of immunoreactive cells in control subjects, IBS-total patients, and IBSsubtype patients

From: Abnormalities in ileal stem, neurogenin 3, and enteroendocrine cells in patients with irritable bowel syndrome

Cell type

Controls

IBS-total

IBS-D

IBS-M

IBS-C

Msi-1

6.2 ± 0.2

4.8 ± 0.2***

4.3 ± 0.3***

4.8 ± 0.2**

5.1 ± 0.2*

NEUROG3

16.8 ± 0.8

7.6 ± 0.3***

8.0 ± 0.6***

6.7 ± 0.5***

8.1 ± 0.7***

CgA

64.3 ± 3.6

28.8 ± 2.11***

29.2 ± 3.5***

25.7 ± 3.6***

30.3 ± 3.7***

Serotonin

40.8 ± 3.5

12.0 ± 1.3***

10.7 ± 2.0***

11.1 ± 2.0***

13.9 ± 2.5***

PYY

26.6 ± 1.6

33.5 ± 1.4*

27.6 ± 1.4

33.5 ± 2.4

41.9 ± 2.3**

  1. *P < 0.05, **P < 0.01, ***P < 0.001 vs. controls (Dunn’s multiple-comparisons test)
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BMC Gastroenterology

ISSN: 1471-230X

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