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Table 3 Adjusted cox models of CRC risk stratified by sex

From: Risk of colorectal cancer among immigrants to Ontario, Canada

Variable Females Males
Univariate HR (95% CI) Multivariate HR (95% CI) Multivariate HR (95% CI) with interaction Univariate HR (95% CI) Multivariate HR (95% CI) Multivariate HR (95% CI) with interaction
Overall
 Immigrant 0.63 (0.60, 0.66) 0.64 (0.61, 0.67)   0.59 (0.56, 0.62) 0.59 (0.56, 0.62)  
 Nonimmigrant controls Reference Reference   Reference Reference
Age at index
 40 - 49 Reference Reference Reference Reference Reference Reference
 50 - 59 2.35 (2.25, 2.45) 2.35 (2.25, 2.45) 2.35 (2.25, 2.45) 2.59 (2.50, 2.70) 2.60 (2.50, 2.70) 2.60 (2.50, 2.70)
 60 - 69 4.54 (4.36, 4.73) 4.53 (4.35, 4.72) 4.53 (4.35, 4.72) 4.94 (4.77, 5.12) 4.94 (4.77, 5.12) 4.94 (4.77, 5.12)
 70 - 74 6.54 (6.19, 6.91) 6.52 (6.17, 6.88) 6.52 (6.17, 6.88) 6.99 (6.62, 7.37) 6.98 (6.62, 7.37) 6.98 (6.62, 7.37)
  > = 75 8.63 (8.11, 9.17) 8.63 (8.12, 9,17) 8.63 (8.12, 9.17) 8.46 (7.93, 9.03) 8.47 (7.94, 9.04) 8.47 (7.94, 9.04)
Immigrant < = 10 years since index date 0.62 (0.58, 0.66)   0.63 (0.59, 0.67) 0.55 (0.52, 0.59)   0.55 (0.52, 0.59)
Controls <= 10 years since index date Reference   Reference Reference   Reference
Immigrant > 10 years since index date 0.65 (0.58, 0.73)   0.66 (0.59, 0.74) 0.64 (0.57, 0.72)   0.63 (0.57, 0.71)
Controls <= 10 years since index date Reference   Reference Reference   Reference
Age adjusted models for world region of birth
 East Asia and Pacific
  Immigrant < = 10 years since index date 0.70 (0.63, 0.78)   0.72 (0.65, 0.80) 0.70 (0.64, 0.78)   0.72 (0.65, 0.79)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
  Immigrant > 10 years since index date 0.79 (0.66, 0.95)   0.80 (0.67, 0.96) 0.74 (0.62, 0.89)   0.73 (0.61, 0.87)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
 Europe and Central Asia
  Immigrant< = 10 years since index date 1.10 (0.98, 1.23)   1.09 (0.97, 1.22) 1.02 (0.90, 1.15)   1.01 (0.90, 1.14)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
  Immigrant > 10 years since index date 0.96 (0.77, 1.18)   0.96 (0.78, 1.19) 1.05 (0.85, 1.30)   1.04 (0.84, 1.29)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
 Latin America and the Caribbean
  Immigrant < = 10 years since index date 0.58 (0.47, 0.71)   0.59 (0.48, 0.72) 0.45 (0.35, 0.57)   0.46 (0.36, 0.58)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
  Immigrant > 10 years since index date 0.56 (0.39, 0.81)   0.58 (0.41, 0.84) 0.46 (0.30, 0.71)   0.46 (0.30, 0.71)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
 Middle East and North Africa
  Immigrant< = 10 years since index date 0.52 (0.40, 0.67)   0.52 (0.40, 0.68) 0.49 (0.39, 0.61)   0.48 (0.38, 0.60)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
  Immigrant > 10 years since index date 0.54 (0.33, 0.87)   0.54 (0.34, 0.88) 0.72 (0.49, 1.07)   0.70 (0.47, 1.03)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
 South Asia
  Immigrant < = 10 years since index date 0.23 (0.19, 0.28)   0.24 (0.19, 0.29) 0.17 (0.14, 0.21)   0.18 (0.14, 0.22)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
  Immigrant > 10 years since index date 0.24 (0.17, 0.35)   0.25 (0.17, 0.37) 0.28 (0.20, 0.40)   0.28 (0.20, 0.40)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
 Sub-saharan Africa
  Immigrant < = 10 years since index date 0.27 (0.17, 0.43)   0.27 (0.17, 0.43) 0.39 (0.26, 0.59)   0.38 (0.25, 0.57)
  Controls <= 10 years since index date Reference   Reference Reference   Reference
  Immigrant > 10 years since index date 0.56 (0.26, 1.18)   0.56 (0.26, 1.18) 0.78 (0.40, 1.53)   0.75 (0.38, 1.48)
  Controls <= 10 years since index date Reference   Reference Reference   Reference