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Fig. 3 | BMC Gastroenterology

Fig. 3

From: Regulation of apoptosis is impaired in atrophic gastritis associated with gastric cancer

Fig. 3

Immunohistochemical TUNEL staining in normal mucosa, AG/IM without cancer and GC. TUNEL was expressed in non-transformed gastric mucosa (upper left) but its staining was significantly increased in presence of atrophic (upper right) and metaplastic (down left) or neoplastic changes of the mucosa (down right). The TUNEL staining differed significantly between the analysed groups (Kruskal-Wallis H = 37.11, p = 0.0001) and increased progressively from controls to AG and IM in patients without gastric cancer (Mann-Whitney’s U test p = 0.001) and to intestinal type gastric cancer (Mann-Whitney’s U test p = 0.007)

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