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Table 3 The results of Gene Ontology enrichment analysis of target genes of microRNAs in module blue

From: miR-363-5p as potential prognostic marker for hepatocellular carcinoma indicated by weighted co-expression network analysis of miRNAs and mRNA

Function ontology p value Description
Alternative splicing 2.90E-05 Protein for which at least two isoforms exist due to distinct pre-mRNA splicing events.
Phosphotransferase 3.90E-03 Protein involved in the phosphotransferase system, the major carbohydrate transport system in bacteria. This phosphotransferase system catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to incoming sugar substrates concomitant with their translocation across the cell membrane.
Coiled coil 5.30E-03 Protein which contains at least one coiled coil domain, a type of secondary structure composed of two or more alpha helices which entwine to form a cable structure. In proteins, the helical cables serve a mechanical role in forming stiff bundles of fibres.
Immune response 9.00E-03 Protein involved in immunity, any immune system process that functions in the response of an organism to a potential internal or invasive threat. The vertebrate immune system is formed by the innate immune system (composed of phagocytes, complement, antimicrobial peptides, etc) and by the adaptive immune system which consists of T- and B-lymphocytes.
Transferase 1.40E-02 Enzyme that transfers a chemical group, e.g. a methyl group or a glycosyl group from one compound (donor) to another compound (acceptor).