Parameter | Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | Performance a |
---|---|---|---|---|---|
Analysis with the imperfect gold standard methodology: scenario 1 | |||||
dCAP | 0.72 (0.64–0.79) | 0.98 (0.97–0.98) | 0.93 (0.90–0.96) | 0.89 (0.86–0.92) | 0.70 |
Ultrasound | 0.46 (0.42–0.50) | 0.91 (0.89–0.92) | 0.68 (0.62–0.73) | 0.80 (0.78–0.81) | 0.37 |
Fatty Liver index | 0.73 (0.72–0.74) | 0.27 (0.25–0.28) | 0.30 (0.29–0.31) | 0.7 (0.69–0.7) | 0 |
BMI + AST and/or ALT | 0.75 (0.73–0.77) | 0.57 (0.55–0.60) | 0.43 (0.41–0.45) | 0.84 (0.82–0.86) | 0.22 |
Analysis with the imperfect gold standard methodology: scenario 2 | |||||
dCAP | 0.72 (0.69–0.78) | 1.00 (1.00–1.00) | 0.99 (0.99–1) | 0.89 (0.88–0.91) | 0.72 |
Ultrasound | 0.43 (0.38–0.50) | 0.99 (0.99–1.00) | 0.96 (0.94–0.98) | 0.8 (0.78–0.82) | 0.42 |
Hepatic Steatosis Index | 0.85 (0.84–0.85) | 0.33 (0.32–0.35) | 0.35 (0.34–0.36) | 0.83 (0.82–0.84) | 0.18 |
BMI + AST and/or ALT | 0.73 (0.69–0.77) | 0.73 (0.69–0.77) | 0.54 (0.49–0.58) | 0.86 (0.84–0.88) | 0.54 |