Table 2 Univariate & multivariate analyses of prognosis parameters for OS in 347 advanced gastric cancer patients

FBXW7 (low vs.high)

0.688

0.527–0.899

0.006*

0.622

0.501–0.875

0.004*

Age (<60 vs. ≥60)

1.441

0.870–1.494

0.340

1.008

0.822–1.440

0.557

Gender (male vs. female)

0.942

0.712–1.246

0.674

0.979

0.734–1.306

0.887

Size (≤5 cm vs. >5 cm)

1.994

1.522–2.612

0.000*

1.539

1.156–2.048

0.003*

Tumor differentiation (well/moderate vs. poor)

1.426

1.406–1.945

0.025*

0.922

0.665–1.280

0.629

T stage (T2 vs. T3/T4)

3.104

2.253–4.277

0.000*

1.504

0.948–2.385

0.083

N stage (absent vs. present)

1.701

1.494–1.936

0.000*

1.404

1.158–1.701

0.001*

Vessel invasion (absent vs. present)

2.115

1.555–2.876

0.000*

1.372

0.975–1.931

0.070

Nerve invasion (absent vs. present)

1.819

1.292–2.561

0.001*

1.183

0.813–1.722

0.380

Chemotherapy (with or without)

0.707

0.509–0.982

0.038*

0.793

0.562–1.119

0.187