Table 1 Correlation of FBXW7expression and clinicopathological characteristics in 546 gastric adenocarcinoma patients
Number | FBWX7 low expression | FBWX7 high expression | P-Value | |
|---|---|---|---|---|
Age | 0.182 | |||
≤ 60 | 253 | 118 (46.6%) | 135 (53.4%) | |
> 60 | 293 | 120 (41.0%) | 173 (59.0%) | |
Gender | 0.473 | |||
Male | 351 | 149 (42.5%) | 202 (57.5%) | |
Female | 195 | 89 (45.6%) | 106 (54.4%) | |
Tumor size | 0.001* | |||
≤ 5 cm | 348 | 133 (38.2%) | 215 (61.8%) | |
> 5 cm | 198 | 105 (53.0%) | 93 (47.0%) | |
Histological grade | 0.001* | |||
Well | 16 | 5 (31.3%) | 11 (68.7%) | |
Moderate | 140 | 44 (31.4%) | 96 (68.6%) | |
Poor | 390 | 189 (48.5%) | 201 (51.5%) | |
Depth of tumor (pT) | ||||
T1 | 85 | 37 (43.5%) | 48 (56.5%) | 0.256 |
T2 | 76 | 27 (35.5%) | 49 (64.5%) | |
T3 | 149 | 61 (40.9%) | 88 (59.1%) | |
T4 | 236 | 113 (47.9%) | 123 (52.1%) | |
Nodal stage (pN) | 0.040* | |||
N0 | 207 | 91 (44.0%) | 116 (56.0%) | |
N1 | 100 | 32 (32.0%) | 68 (68.0%) | |
N2 | 107 | 48 (44.9%) | 59 (55.1%) | |
N3 | 132 | 67 (50.8%) | 65 (49.2%) | |
Vessel invasion | 0.003* | |||
Negative | 444 | 180 (40.5%) | 264 (59.5%) | |
Positive | 102 | 58 (56.9%) | 44 (43.1%) | |
Nerve invasion | 0.148 | |||
Negative | 479 | 203 (42.4%) | 276 (57.6%) | |
Positive | 67 | 35 (52.2%) | 32 (47.8%) |