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Table 2 Average HBV DNA and ALT levels before and after treatment

From: Telbivudine treatment started in early and middle pregnancy completely blocks HBV vertical transmission

 

Group A

Group B

Group C

P

Sujects, n

62

61

65

 

HBV DNA viral load, log10 copies/ml

 Before treatment

7.79 ± 0.22

7.75 ± 0.19

7.74 ± 0.22

0.373

 Before delivery

0.51 ± 1.44

0.49 ± 1.26

7.64 ± 0.24

<0.001

 Postpartum 12 weeks

0.38 ± 1.12

0.35 ± 1.28

7.85 ± 0.27

<0.001

ALT levels, IU/mL

 Before treatment

125.3 ± 57.6

132.3 ± 52.9

128.5 ± 48.7

0.766

 Before delivery

63.8 ± 15.6

59.5 ± 13.4

112.7 ± 24.1

<0.001

 Postpartum 12 weeks

48.9 ± 18.2

51.3 ± 20.1

84.1 ± 32.5

<0.001