Fig. 4

Remission maintenance rates. a Comparison by drug. Cochran-Mantel-Haenszel test. Adjustment factors: age (≤60 years, ≥61 years), classification by the extent of lesion, classification by clinical course, smoking habit, concomitant use of drugs for UC other than probiotics/cytapheresis therapy, duration of disease, duration of remission maintenance until enrollment (0 for patients in the active stage at enrollment). b Comparison between Pentasa® Tablets at 4000 mg/day in 2 divided doses and Asacol® Tablets at 3600 mg/day in 3 divided doses. Cochran-Mantel-Haenszel test. Adjustment factors: age (≤60 years, ≥61 years), classification by the extent of lesion, classification by clinical course, smoking habit, concomitant use of drugs for UC other than probiotics/cytapheresis therapy, duration of disease, duration of remission maintenance until enrollment (0 for patients in the active stage at enrollment). c Comparison between Pentasa® Tablets at 2000 mg/day in 1 dose and Asacol® Tablets 2400 mg/day in 3 divided doses. Cochran-Mantel-Haenszel test. Adjustment factors: age (≤60 years, ≥61 years), classification by the extent of lesion, classification by clinical course, smoking habit, concomitant use of drugs for UC other than probiotics/cytapheresis therapy, duration of disease, duration of remission maintenance until enrollment (0 for patients in the active stage at enrollment). d Comparison by the extent of lesion. Cochran-Mantel-Haenszel test. Adjustment factors: age (≤60 years, ≥61 years), classification by clinical course, smoking habit, concomitant use of drugs for UC other than probiotics/cytapheresis therapy, duration of disease, duration of remission maintenance until enrollment (0 for patients in the active stage at enrollment). e Comparison by clinical course. Cochran-Mantel-Haenszel test. Adjustment factors: age (≤60 years, ≥61 years), classification by the extent of lesion, smoking habit, concomitant use of drugs for UC other than probiotics/cytapheresis therapy, duration of disease, duration of remission maintenance until enrollment (0 for patients in the active stage at enrollment)