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Table 5 Multiple regression analysis of characteristics of the patients divided by AGI grade

From: Association between acute gastrointestinal injury and biomarkers of intestinal barrier function in critically ill patients

 

Grade II

 

Grade III

 

Grade IV

 

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

APACHE II score

1.017 (0.884–1.168)

0.817

1.754 (1.225–2.511)

0.002

1.493 (1.079–2.066)

0.015

IAP (mm Hg)

1.174 (0.890–1.550)

0.257

1.622 (1.111–2.369)

0.012

1.518 (1.066–2.162)

0.021

i-FABP (pg/mL)

0.993 (0.987–1.000)

0. 067

0.996 (0.985–1.007)

0. 454

0.997 (0.987–1.007)

0.575

LPS (pg/mL)

1.286 (0.846–1.956)

0.239

0.609 (0.238–1.559)

0.301

0.923 (0.497–1.714)

0.800

d-la (μmol/L)

1.059 (1.005–1.117)

0.033

1.155 (1.052–1.268)

0.003

1.088 (1.013–1.168)

0.021

  1. Variables were compared using multinomial logistic regression for the multiple analysis; Grade I is the reference for Grades II, III, and IV
  2. AGI acute gastrointestinal injury, APACHE acute physiology and chronic health evaluation, CI confidence interval, d -la d-lactate, IAP intra-abdominal pressure, i-FABP intestinal fatty acid–binding protein, LPS lipopolysaccharide, OR odds ratio