Fig. 1

Change of HBV DNA during follow-up period. a The changes in the mean hepatitis B virus (HBV) DNA levels from baseline through week 48. The overall mean changes at weeks 12, 24 and 48 were −4.26 log₁₀ IU/mL, −4.89 log₁₀ IU/mL and −5.12 log₁₀ IU/mL, respectively. b The mean reduction in serum HBV DNA levels from baseline to week 48 was similar in tenofovir and entecavir group (−5.22 vs. −5.01 log₁₀ IU/mL, P = 0.559) by repeated measure analysis