Skip to main content

Advertisement

Table 3 Exposure to angiotensin receptor blockers (ARB) and severity of acute pancreatitis, estimated by odds ratios (OR) with 95% confidence intervals (CI)

From: Angiotensin II receptor blockers and risk of acute pancreatitis - a population based case–control study in Sweden

Exposure Controls Mild acute pancreatitis Moderate acute pancreatitis Severe acute pancreatitis
N (%) N (%) N (%) N (%)
Total, n (%) 61,637 (100) 2,783 (100) 1,542 (100) 1,814 (100)
ARB 56,542 (92) 2,514 (90) 1,403 (91) 1,632 (90)
Never use
Current use 4,715 (8) 249 (9) 131 (8.5) 168 (9)
 Model 1 OR (95 % CI) 1 (Reference) 1 · 25 (1 · 10–1 · 44) 1 · 08 (0 · 90–1 · 30) 1 · 18 (1 · 00–1 · 39)
 Model 2 (OR (95 % CI) 0 · 86 (0 · 75–0 · 99) 0 · 73 (0 · 61–0 · 88) 0 · 76 (0 · 64–0 · 89)
 Model 3 OR (95 % CI) 0 · 81 (0 · 70–0 · 94) 0 · 71 (0 · 58–0 · 87) 0 · 71 (0 · 59–0 · 85)
Past use 380 (1) 20 (0.5) 8 (0.5) 14 (1)
 Model 1 OR (95 % CI) 1 (Reference) 1 · 24 (0 · 79–1 · 95) 0 · 82 (0 · 41–1 · 66) 1 · 23 (0 · 72–2 · 10)
 Model 2 OR (95 % CI) 0 · 85 (0 · 54–1 · 33) 0.56 (0.28–1.13) 0 · 79 (0 · 49–1 · 35)
 Model 3 OR (95 % CI) 0 · 75 (0 · 46–1 · 22) 0.53 (0 · 26–1 · 08) 0 · 75 (0 · 42–1 · 29)
  1. 1) Adjusting for sex, age and calendar year
  2. 2) Adjusting for sex, age, calendar year and presence of cardiovascular disorder
  3. 3) Adjusting for sex, age, calendar year, education, chronic obstructive pulmonary disease, diabetes, alcohol related disease, cardiovascular disorder, and number of distinct medications