Therapeutic effects of different doses of polyethylene glycosylated porcine glucagon-like peptide-2 on ulcerative colitis in male rats

Table 2 Effects of polyethylene glycosylated (PEGylated) porcine glucagon-like peptide-2 (pGLP-2) on growth performance of colitis rats

Groups	Body weight change, %	Intestinal length, cm	Colonic length, cm	Intestinal weight (mg)/body weight (g)	Colonic weight (mg)/body weight (g)
Control	30.48 ± 3.44^a	94.72 ± 4.93	15.69 ± 1.90^a	30.61 ± 2.22	11.19 ± 1.90^b
Dextran sodium sulphate (DSS)	11.90 ± 5.04^c	92.88 ± 9.78	12.40 ± 1.94^b	35.19 ± 1.22	9.15 ± 1.79^b
DSS + PEG–pGLP-2(L)	21.45 ± 2.00^b	94.50 ± 7.07	14.74 ± 1.90^a	34.51 ± 3.09	14.13 ± 2.77^a
DSS + PEG–pGLP-2(M)	21.46 ± 4.65^b	99.10 ± 8.03	14.48 ± 1.42^ab	38.91 ± 4.23	14.22 ± 0.38^a
DSS + PEG–pGLP-2(H)	20.63 ± 3.4^b	99.56 ± 6.82	13.42 ± 0.80^ab	35.87 ± 1.73	11.52 ± 0.64^b

Data are expressed as means ± SD; no significant difference exists in that with no letter or the same letters (p > 0.05), and different letters (p < 0.05) indicate statistically significant difference

ISSN: 1471-230X