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Fig. 5 | BMC Gastroenterology

Fig. 5

From: The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in patients with Crohn’s disease

Fig. 5

Receiver operating characteristic (ROC) curves of apoptosis inhibitor of macrophage (AIM) and anti-Saccharomyces cerevisiae antibodies (ASCA) for the diagnosis of Crohn’s disease (CD). The ROC curves for AIM and ASCA were obtained by plotting sensitivity versus 1-specificity. Sensitivity and specificity were each calculated using ELISA. AIM had a sensitivity of 68.2%, a specificity of 80.6%, a positive predictive value (PPV) of 65.9%, a negative predictive value (NPV) of 80.6%, and an accuracy of 72.5% for distinguishing CD from ulcerative colitis, while the corresponding values for ASCA were 60.5, 72.5, 62.2, 71.1, and 67.4%, respectively

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