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Table 2 Examination of relationship of Claudin-2 high expression and clinicopathologic characteristics in esophageal adenocarcinoma

From: High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5

Covariate   High-expression Non-high expression P value
Age Mean (SD) 63.9 (11.1) 63.6 (11.4) 0.9128
Range 34 – 84 40 – 85
Gender Male 75 24 0.2922
Female 11 1
Lymph node metastasis # (+) nodes 4.2 (5.2) 3.7 (4.5) 0.6286
Survival time   39.51 (41.55) 33.32 (35.88) 0.6385
Tumor location
Fisher’s Test
DISTAL 19 4 0.7162
GEJ 64 21
Other 3 0
Tumor location
Fisher’s Test
DISTAL 19 4 0.8078
GEJ 64 21
MID 2 0
PROXIMAL 1 0
TNM Stage
Fisher’s Test
1 1 0 0.6444
2 10 1
3 21 8
4 54 16
T stage
Fisher’s Test
1 2 0 0.4647
2 13 1
3 17 6
4 54 18
N stage
Fisher’s Test
0 20 6 0.7982
1 42 13
2 14 5
3 10 1
Differentiation
(missing = 2)
Fisher’s Test
Poor 57 15 0.7075
Moderate 23 9
Well 4 1