Table 2 Examination of relationship of Claudin-2 high expression and clinicopathologic characteristics in esophageal adenocarcinoma
Covariate | Â | High-expression | Non-high expression | P value |
|---|---|---|---|---|
Age | Mean (SD) | 63.9 (11.1) | 63.6 (11.4) | 0.9128 |
Range | 34 – 84 | 40 – 85 | ||
Gender | Male | 75 | 24 | 0.2922 |
Female | 11 | 1 | ||
Lymph node metastasis | # (+) nodes | 4.2 (5.2) | 3.7 (4.5) | 0.6286 |
Survival time | Â | 39.51 (41.55) | 33.32 (35.88) | 0.6385 |
Tumor location Fisher’s Test | DISTAL | 19 | 4 | 0.7162 |
GEJ | 64 | 21 | ||
Other | 3 | 0 | ||
Tumor location Fisher’s Test | DISTAL | 19 | 4 | 0.8078 |
GEJ | 64 | 21 | ||
MID | 2 | 0 | ||
PROXIMAL | 1 | 0 | ||
TNM Stage Fisher’s Test | 1 | 1 | 0 | 0.6444 |
2 | 10 | 1 | ||
3 | 21 | 8 | ||
4 | 54 | 16 | ||
T stage Fisher’s Test | 1 | 2 | 0 | 0.4647 |
2 | 13 | 1 | ||
3 | 17 | 6 | ||
4 | 54 | 18 | ||
N stage Fisher’s Test | 0 | 20 | 6 | 0.7982 |
1 | 42 | 13 | ||
2 | 14 | 5 | ||
3 | 10 | 1 | ||
Differentiation (missing = 2) Fisher’s Test | Poor | 57 | 15 | 0.7075 |
Moderate | 23 | 9 | ||
Well | 4 | 1 |