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Table 1 Rate of Claudin-2 high expression in EAC and precancerous lesions and squamous cell carcinoma

From: High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5

Histological Type Total (n) High-expression (%) Non-high expression (%)
Adenocarcinoma 111 86 (77%) 25 (23%)
High grade dysplasia 13 5 (38%) 8 (62%)
Low grade dysplasia 28 17 (61%) 11 (39%)
Barrett’s esophagus 39 18 (46%) 21 (54%)
Columnar cell metaplasia 65 29 (45%) 36 (55%)
Squamous epithelium 76 11 (14%) 65 (86%)
Squamous cell carcinoma 26 23 (88%) 3 (12%)