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Table 1 Rate of Claudin-2 high expression in EAC and precancerous lesions and squamous cell carcinoma

From: High expression of Claudin-2 in esophageal carcinoma and precancerous lesions is significantly associated with the bile salt receptors VDR and TGR5

Histological Type

Total (n)

High-expression (%)

Non-high expression (%)

Adenocarcinoma

111

86 (77%)

25 (23%)

High grade dysplasia

13

5 (38%)

8 (62%)

Low grade dysplasia

28

17 (61%)

11 (39%)

Barrett’s esophagus

39

18 (46%)

21 (54%)

Columnar cell metaplasia

65

29 (45%)

36 (55%)

Squamous epithelium

76

11 (14%)

65 (86%)

Squamous cell carcinoma

26

23 (88%)

3 (12%)