Variables | Cirrhosis n = 91 | Non- cirrhosis n = 53 | P-value |
---|---|---|---|
Sex (male/female), n | 89/2 | 46/7 | 0.274 |
Age (years; mean ± SD) | 53.2 ± 9.2 | 52.1 ± 8.1 | 0.463 |
Overweight (BMI 25.0-29.99 kg/m2), n (%) | 15 (16.5) | 10 (18.9) | 0.716 |
Obesity (BMI ≥ 30 kg/m2), n (%) | 3 (3.3) | 2 (3.8) | 0.880 |
Hypertension, n (%) | 12 (13.2) | 6 (11.3) | 0.744 |
Diabetes mellitus, n (%) | 10 (11.0) | 4 (7.5) | 0.501 |
Hepatitis B surface antigen, n (%) | 79 (63.8) | 22 (37.2) | <0.001 |
Alcohol use, n (%) | 24 (26.4) | 5 (9.4) | 0.015 |
Total bilirubin (μmol/L; mean ± SD) | 17.8 ± 8.8 | 15.4 ± 4.1 | 0.090 |
Albumin (g/L; mean ± SD) | 40.5 ± 5.3 | 41.2 ± 4.6 | 0.417 |
Aspartate aminotransferase (IU/L; mean ± SD) | 51.2 ± 35.3 | 39.6 ± 22.3 | 0.021 |
Alanine aminotransferase (IU/L; mean ± SD) | 54.5 ± 50.6 | 41.8 ± 36.7 | 0.043 |
Child-Pugh (A/B), n | 85/6 | 53/0 | 0.056 |
Tumor diameter (cm; mean ± SD) | 4.9 ± 2.5 | 6.7 ± 2.8 | <0.001 |
Tumor number (St/Mt), n | 82/9 | 46/7 | 0.541 |
Encapsulation, n (%) | 34 (37.4) | 15 (28.3) | 0.268 |
Vascular invasion, n (%) | 41 (45.1) | 27 (50.9) | 0.495 |
Bile duct invasion, n (%) | 17 (18.7) | 11(20.8) | 0.762 |
Lymph node involvement, n (%) | 12 (13.2) | 8 (15.1) | 0.750 |
Alpha-fetoprotein ≥ 20 ng/mL, n (%) | 56 (61.5) | 22 (41.5) | 0.020 |
Carbohydrate antigen 19–9 ≥ 37 U/mL, n (%) | 31 (34.1) | 21 (39.6) | 0.503 |
Carcinoembryogenic antigen ≥ 5 ng/mL, n (%) | 7 (7.7) | 3 (5.7) | 0.644 |