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Table 7 Predictors of HRQoL of DAAs therapy users prior, during and at the end of therapy

From: Health-related quality of Life in patients with chronic hepatitis C receiving Sofosbuvir-based treatment, with and without Interferon: a prospective observational study in Egypt

Model Summary of the model Unstandardized Coefficients Standardized Coefficients    95.0% Confidence Interval for B Collinearity Statistics
R R2 AdjR2 B Beta t Sig. Lower Bound Upper Bound Tolerance VIF
T0 (Constant) .63 .39 .38 15.79   4.46 .000 8.69 22.89   
Depression-T0 1.11 .41 3.13 .003 .39 1.83 .65 1.53
Anxiety-T0 .98 .29 2.21 .032 .09 1.87 .65 1.53
T1 (Constant) .88 .78 .76 18.13   1.45 .153 -6.95 43.21   
Stress-T1 1.39 .44 4.04 .000 .70 2.09 .36 2.76
HRQoL-T0 .37 .31 3.54 .001 .16 .58 .56 1.77
Anxiety-T1 .91 .24 2.27 .028 .10 1.72 .37 2.66
BMI-T1 -2.39 -.47 -2.82 .007 -4.11 -.69 .16 6.25
BMI-T0 1.91 .35 2.12 .040 .09 3.730 .15 6.32
T2 (Constant) .91 .83 .81 34.92   3.42 .002 13.97 55.87   
HRQoL-T1 .68 .72 5.52 .000 .43 .93 .36 2.72
Anxiety-T2 2.11 .66 5.27 .000 1.29 2.93 .46 2.17
MSPSS-T2 -12.81 -.25 -3.09 .005 -21.33 -4.29 .93 1.06
Anxiety-T1 -1.14 -.33 -2.11 .044 -2.25 -.03 .25 3.91
  1. HRQoL-T0 health-related quality of life time 0, BMI-T1 body mass index time 1, BMI-T0 body mass index time 0, HRQoL-T1 health-related quality of life time 1, MSPSS-T2 Multidimensional Scale of Perceived Social Support time 2
  2. P value significant at two tailed