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Table 5 PROs prior, during and at the end of treatment among dual and triple users

From: Health-related quality of Life in patients with chronic hepatitis C receiving Sofosbuvir-based treatment, with and without Interferon: a prospective observational study in Egypt

  Type of therapy Independent-samples Mann-Whitney U Test
Dual N =31 Triple N = 31 P value Sig. (2-tailed)
Baseline X ± SD  
 BMI-T0 31.26 ± 4.16 29.92 ± 4.26 .31
 HRQoL-T0 32.54 ± 21.23 30.74 ± 17.67 .85
 Symptom Severity-T0 23.32 ± 13.14 22.93 ± 11.24 .97
 Symptom Hindrance-T0 9.22 ± 9.09 7.80 ± 7.50 .64
 MSPSS-T0 2.22 ± .57 2.49 ± .39 .05
 Depression-T0 9.12 ± 7.51 8.09 ± 6.92 .59
 Anxiety-T0 6.41 ± 5.83 7.51 ± 6.03 .53
 Stress-T0 8.64 ± 6.61 10.80 ± 7.63 .29
After 5/6 weeks X ± SD
 BM-IT1 31.24 ± 4.47 29.60 ± 4.50 .16
 HRQoL-T1 31.06 ± 24.06 41.54 ± 21.62 .04
 Symptom Severity-T1 21.77 ± 15.09 28.51 ± 12.72 .05
 Symptom Hindrance-T1 9.29 ± 9.64 13.03 ± 9.67 .09
 MSPSS-T1 2.34 ± .55 2.54 ± .38 .23
 Depression-T1 9.12 ± 7.67 9.48 ± 7.15 .72
 Anxiety-T1 5.64 ± 5.77 9.19 ± 6.16 .01
 Stress-T1 9.00 ± 7.46 11.87 ± 7.09 .11
 INDEXSCORE-T1 15.74 ± .77 15.45 ± 1.45 .87
At the end of therapy X ± SD
 HRQoL-T2 26.60 ± 17.01 37.53 ± 20.47 .15
 Symptom Severity-T2 18.20 ± 12.50 26.57 ± 12.29 .06
 Symptom Hindrance-T2 8.40 ± 5.10 10.96 ± 8.72 .52
 MSPSS-T2 2.40 ± .40 2.41 ± .40 .84
 Depression-T2 6.20 ± 6.49 10.03 ± 6.40 .10
 Anxiety-T2 4.50 ± 3.53 7.76 ± 6.61 .27
 Stress-T2 6.40 ± 5.16 11.03 ± 6.99 .08
 INDEXSCORE-T2 15.90 ± .31 15.30 ± 1.46 .41
  1. BMI-T0 body mass index time 0, HRQoL-T0 health-related quality of life time 0, MSPSS-T0 Multidimensional Scale of Perceived Social Support time 0, BMI-T1 body mass index time 1, HRQoL-T1 health-related quality of life time 1, MSPSS-T1 Multidimensional Scale of Perceived Social Support time 1, INDEXSCORE-T1 The total index score of the Center for Adherence Support Evaluation (CASE) Index time 1, HRQoL-T2 health-related quality of life time 2, MSPSS-T2 Multidimensional Scale of Perceived Social Support time 2, INDEXSCORE-T2 The total index score of the Center for Adherence Support Evaluation (CASE) Index time 2
  2. P value significant at two tailed