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Table 4 Comparisons of second-line treatment after failure of first-line eradication therapy

From: Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication

 

TT → BCQT-7

TT → BCQT-14

SET → BCQT-14

P value

Eradication rate, % (n)

 ITT

71 (22/31)

85.3 (64/75)

72.7 (16/22)

0.162

 PP

84 (21/25)

95.5 (64/67)

84.2 (16/19)

0.076

Compliance > 80%, % (n)

80.6 (25)

89.3 (67)

86.4 (19)

0.511

Adverse events, % (n)

25.8 (8)

22.7 (17)

18.2 (4)

0.839

  1. TT triple therapy, SET sequential therapy, BCQT-7 bismuth-containing quadruple therapy for 7 days, BCQT-14 bismuth-containing quadruple therapy for 14 days, ITT intention to treat, PP per protocol