Table 1 Baseline clinical characteristics
From: Triple therapy versus sequential therapy for the first-line Helicobacter pylori eradication
TT | SET | P value | |
|---|---|---|---|
N = 872 (74.3%) | N = 302 (25.7%) | ||
Age (mean ± SD) | 52.26 ± 13.52 | 51.83 ± 12.17 | 0.607 |
Male | 477 (54.7) | 192 (63.6) | 0.007 |
Residence | 0.510 | ||
Seoul | 695 (79.7) | 246 (81.5) | |
Another area | 177 (20.3) | 56 (18.5) | |
Smoking | 217 (24.9) | 113 (37.4) | <0.001 |
Alcohol | 389 (41.3) | 91 (39.2) | <0.001 |
Diabetes mellitus | 98 (11.2) | 33 (10.9) | 0.882 |
Hypertension | 185 (21.2) | 71 (23.5) | 0.405 |
Chronic kidney disease | 12 (1.4) | 4 (1.3) | 0.999 |
Chronic liver disease | 24 (2.8) | 7 (2.3) | 0.685 |
Ischemic heart disease | 23 (2.6) | 12 (4.0) | 0.239 |
Compliance > 80% | 707 (81.1) | 256 (84.8) | 0.150 |
H. pylori test | <0.001 | ||
Histology | 293 (33.6) | 182 (60.3) | |
Rapid urease test | 586 (64.9) | 116 (38.4) | |
Urea breath test | 8 (0.9) | 2 (0.7) | |
Serology | 5 (0.6) | 2 (0.7) | |
Endoscopic diagnosis | |||
Chronic gastritis | 201 (23.1) | 31 (10.3) | <0.001 |
Atrophy or metaplasia | 332 (38.1) | 141 (46.7) | 0.009 |
Gastric ulcer | 274 (31.4) | 119 (39.4) | 0.011 |
Duodenal ulcer | 331 (38.0) | 89 (29.5) | 0.008 |
Duodenitis | 52 (6.0) | 18 (6.0) | 0.998 |
Indication of H. pylori eradication | |||
Peptic ulcer disease | 522 (59.9) | 148 (49.0) | 0.001 |
Endoscopic resection of EGC | 21 (2.4) | 24 (7.9) | <0.001 |
Endoscopic resection of adenoma | 36 (4.1) | 24 (7.9) | 0.009 |
MALT lymphoma | 4 (0.5) | 2 (0.7) | 0.651 |
H. pylori gastritis | 83 (9.5) | 23 (7.6) | 0.320 |
Atrophy or metaplasia | 130 (14.9) | 61 (20.2) | 0.032 |