|
Patient
|
Study
|
Type of Liver failure (LF)
|
Aetiology
|
Precipitating event
|
Age [years]
|
Gender
|
CANONIC [ACLF-grade]
|
Child-Pugh [points]
|
MELD [points]
|
CLIF-SOFA [points]
|
Acute renal failure
|
|---|
|
P1
|
Post-CE
|
acute-on-chronic LF
|
alcoholic
|
SBP
|
59
|
female
|
3
|
12 (C)
|
40
|
12
|
+
|
|
P2
|
Post-CE
|
acute-on-chronic LF
|
alcoholic
|
ASH
|
52
|
female
|
2
|
12 (C)
|
26
|
14
|
+
|
|
P3
|
Post-CE
|
acute-on-chronic LF
|
alcoholic
|
ASH
|
53
|
male
|
3
|
13 (C)
|
37
|
15
|
+
|
|
P4
|
Post-CE
|
acute-on-chronic LF
|
alcoholic
|
Infection
|
61
|
male
|
3
|
11 (C)
|
35
|
15
|
+
|
|
P5
|
Post-CE
|
acute-on-chronic LF
|
alcoholic
|
Ischemia
|
68
|
female
|
3
|
12 (C)
|
24
|
18
|
+
|
|
P6
|
Post-CE
|
acute-on-chronic LF
|
alcoholic
|
ASH, sepsis
|
48
|
female
|
3
|
12 (C)
|
44
|
13
|
+
|
|
P7
|
HEPATICUS-1
|
acute-on-chronic LF
|
alcoholic
|
GI-bleeding
|
54
|
male
|
3
|
14 (C)
|
29
|
14
|
+
|
|
P8
|
HEPATICUS-1
|
acute-on-chronic LF
|
alcoholic
|
GI-bleeding
|
38
|
male
|
3
|
13 (C)
|
32
|
17
|
+
|
|
P9
|
HEPATICUS-1
|
acute-on-chronic LF
|
alcoholic
|
ASH
|
28
|
male
|
3
|
11 (C)
|
34
|
13
|
+
|
|
P10
|
HEPATICUS-2
|
“Secondary” LF
|
Sepsis
|
n.a.
|
66
|
female
|
n.a.
|
n.a.
|
19
|
18
|
+
|
|
P11
|
HEPATICUS-2
|
“Secondary” LF
|
ASH
|
n.a.
|
39
|
male
|
n.a.
|
n.a.
|
39
|
9
|
+
|
|
P12
|
HEPATICUS-2
|
“Secondary” LF
|
Drug-induced
|
n.a.
|
73
|
male
|
n.a.
|
n.a.
|
38
|
15
|
+
|
|
P13
|
HEPATICUS-2
|
“Secondary” LF
|
ASH
|
n.a.
|
56
|
female
|
n.a.
|
n.a.
|
35
|
14
|
+
|
|
P14
|
Post-CE
|
“Secondary” LF
|
Sepsis
|
n.a.
|
67
|
male
|
n.a.
|
n.a.
|
40
|
18
|
+
|
|
Mean ± SD or number [%]
| | | | |
54 ± 13
|
8 male; 6 female
|
2.9 ± 0.3
|
12 ± 1
|
34 ± 7
|
15 ± 3
|
100%
|
-
ASH alcoholic steatohepatitis, SBP spontaneous bacterial peritonitis, MELD model of end-stage liver disease
-
CLIF-SOFA chronic liver-failure sequential organ failure assessment, CANONIC CLIF acute-on-chronic liver failure in cirrhosis
-
n.a not applicable
