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Table 3 The frequency of the occurrence of the CTRC gene polymorphisms (p.G60=; c.180C > T) in the acute pancreatitis patients depending on the severity of the clinical course, etiology and disease relapses

From: CTRC gene polymorphism (p.G60=; c.180 C > T) in acute pancreatitis

Analysis p.G60 = (c.180C > T; rs497078)

No. 299

TT No. 5

CT No. 78

CC No. 216

TT vs. CC

CT vs. CC

TT/CT vs. CC

P value

P value

P value

 Severity of the course

  Mild AP

208

5 (2.4%)

54 (26%)

149 (71.6%)

0.801

0.979

0.908

  Moderate AP

40

-

10 (25%)

30 (75%)

  Severe AP

51

-

14 (27.5%)

37 (72.5%)

 Etiology of AP

  Alcohol

92

3 (3.3%)

21(22.8%)

68 (73.9%

0.418

0.521

0.661

  Gallstones

125

2 (1.6%)

33 (26.4%)

90 (72%)

  Idiopathic

76

 

21 (27.6%)

55 (72.4%)

  Cancer

6

 

3 (50%)

3 (50%)

 Reccurrences of AP

  Yes

111

3 (2.7%)

31 (27.9%)

77 (69.4%)

0.355

0.584

0.473

  1. AP acute pancreatitis, CTRC chymotrypsinogen C