Clinical features | *28 | −3156 GA | 211GA | ||||||
---|---|---|---|---|---|---|---|---|---|
TA 6/6 | TA 6/7 | TA 7/7 | GG | GA | AA | GG | GA | AA | |
Gender | |||||||||
 Male | 64 (84.2) | 10 (13.2) | 2 (2.6) | 64 (84.2) | 10 (13.2) | 2 (2.6) | 49 (64.5) | 23 (30.3) | 4 (5.3) |
 Female | 17 (77.3) | 5 (22.7) | 0 (0.0) | 17 (77.3) | 5 (22.7) | 0 (0.0) | 13 (59.1) | 9 (40.9) | 0 (0.0) |
χ 2, P | 2.046, 0.359 | 2.046, 0.359 | 2.674, 0.263 | ||||||
Age | |||||||||
  < 57 years | 33 (80.5) | 8 (19.5) | 0 (0.0) | 33 (80.5) | 8 (19.5) | 0 (0.0) | 26 (63.4) | 14 (34.1) | 1 (2.4) |
  > 57 years | 48 (84.2) | 7 (12.3) | 2 (3.5) | 48 (84.2) | 7 (12.3) | 2 (3.5) | 36 (63.2) | 18 (31.6) | 3 (5.3) |
χ 2, P | 3.009, 0.222 | 3.009, 0.222 | 0.544, 0.762 | ||||||
Family history | |||||||||
 Yes | 4 (80.0) | 1 (20.0) | 0 (0.0) | 4 (80.0) | 1 (20.0) | 0 (0.0) | 2 (40.0) | 2 (40.0) | 1 (20.0) |
 No | 77 (82.8) | 14 (15.1) | 2 (2.2) | 77 (82.8) | 14 (15.1) | 2 (2.2) | 60 (64.5) | 30 (62.3) | 3 (3.2) |
χ 2, P | 0.283, 0.868 | 0.283, 0.868 | 2.364, 0.307 | ||||||
Alcohol history | |||||||||
 Yes | 29 (90.6) | 3 (9.4) | 0 (0.0) | 29 (90.6) | 3 (9.4) | 0 (0.0) | 21 (65.6) | 9 (28.1) | 2 (6.3) |
 No | 52 (78.8) | 12 (18.2) | 2 (3.0) | 52 (78.8) | 12 (18.2) | 2 (3.0) | 41 (62.1) | 23 (34.8) | 2 (3.0) |
χ 2, P | 3.132, 0.209 | 3.132, 0.209 | 0.861, 0.650 | ||||||
Histological type | |||||||||
 Tubular adenocarcinoma | 60 (80.0) | 13 (17.3) | 2 (2.7) | 60 (80.0) | 13 (17.3) | 2 (2.7) | 54 (72.0) | 19 (25.3) | 2 (2.7) |
 Non-tubular adenocarcinoma | 21 (91.3) | 2 (8.7) | 0 (0.0) | 21 (91.3) | 2 (8.7) | 0 (0.0) | 8 (34.8) | 13 (56.5) | 2 (8.7) |
χ 2, P | 2.308, 0.315 | 2.308, 0.315 | 10.339, 0.006 | ||||||
Differentiation | |||||||||
 Undifferentiated | 13 (86.7) | 2 (13.3) | 0 (0.0) | 13 (86.7) | 2 (13.3) | 0 (0.0) | 6 (40.0) | 7 (46.7) | 2 (13.3) |
 Poor | 51 (85.0) | 8 (13.3) | 1 (1.7) | 51 (85.0) | 8 (13.3) | 1 (1.7) | 41 (68.3) | 18 (30.0) | 1 (1.7) |
 Moderate | 17 (77.3) | 4 (18.2) | 1 (4.5) | 17 (77.3) | 4 (18.2) | 1 (4.5) | 14 (63.6) | 7 (31.8) | 1 (4.5) |
 Well | 0 (0.0) | 1 (100.0) | 0 (0.0) | 0 (0.0) | 1 (100.0) | 0 (0.0) | 1 (100.0) | 0 (0.0) | 0 (0.0) |
χ 2, P | 5.368, 0.498 | 5.368, 0.498 | 6.642, 0.355 | ||||||
Growth patterns | |||||||||
 Expansive | 2 (100.0) | 0 (0.0) | 0 (0.0) | 2 (100.0) | 0 (0.0) | 0 (0.0) | 1 (50.0) | 1 (50.0) | 0 (0.0) |
 Invasive | 56 (78.9) | 13 (18.3) | 2 (2.8) | 56 (78.9) | 13 (18.3) | 2 (2.8) | 47 (66.2) | 21 (29.6) | 3 (4.2) |
 Expansive + invasive | 23 (92.0) | 2 (8.0) | 0 (0.0) | 23 (92.0) | 2 (8.0) | 0 (0.0) | 14 (56.0) | 10 (40.0) | 1 (4.0) |
χ 2, P | 3.800, 0.434 | 3.800, 0.434 | 1.295, 0.862 | ||||||
χ 2, P | 1.239, 0.538 | 1.239, 0.538 | 2.959, 0.228 | ||||||
Depth of invasion | |||||||||
 T1 | 11 (78.6) | 1 (7.1) | 2 (14.2) | 11 (78.6) | 1 (7.1) | 2 (14.2) | 11 (78.6) | 3 (21.4) | 0 (0.0) |
 T2 | 2 (40.0) | 3 (60.0) | 0 (0.0) | 2 (40.0) | 3 (60.0) | 0 (0.0) | 4 (80.0) | 1 (20.0) | 0 (0.0) |
 T3 | 2 (66.7) | 1 (33.3) | 0 (0.0) | 2 (66.7) | 1 (33.3) | 0 (0.0) | 3 (100.0) | 0 (0.0) | 0 (0.0) |
 T4 | 66 (86.8) | 10 (13.2) | 0 (0.0) | 66 (86.8) | 10 (13.2) | 0 (0.0) | 44 (57.9) | 28 (36.8) | 4 (5.3) |
χ 2, P | 14.637, 0.023 | 14.637, 0.023 | 6.870, 0.333 | ||||||
Lymph node metastasis | |||||||||
 N0 | 41 (78.8) | 10 (19.2) | 1 (1.9) | 41 (78.8) | 10 (19.2) | 1 (1.9) | 35 (67.3) | 16 (30.8) | 1 (1.9) |
 N1 | 26 (81.3) | 5 (15.6) | 1 (3.1) | 26 (81.3) | 5 (15.6) | 1 (3.1) | 21 (65.6) | 9 (28.1) | 2 (6.3) |
 N2 | 11 (100) | 0 (0.0) | 0 (0.0) | 11 (100) | 0 (0.0) | 0 (0.0) | 3 (27.3) | 7 (63.6) | 1 (9.1) |
Undetermined | 3 (100.0) | 0 (0.0) | 0 (0.0) | 3 (100.0) | 0 (0.0) | 0 (0.0) | 3 (100.0) | 0 (0.0) | 0 (0.0) |
χ 2, P | 6.082, 0.414 | 6.082, 0.414 | 10.126, 0.119 | ||||||
Distant metastasis | |||||||||
 M0 | 69 (80.2) | 15 (17.4) | 2 (2.3) | 69 (80.2) | 15 (17.4) | 2 (2.3) | 57 (66.3) | 25 (29.1) | 4 (4.7) |
 M1 | 12 (100) | 0 (0.0) | 0 (0.0) | 12 (100) | 0 (0.0) | 0 (0.0) | 5 (41.7) | 7 (58.3) | 0 (0.0) |
χ 2, P | 4.912, 0.086 | 4.912, 0.086 | 4.485, 0.106 | ||||||
TNM staging | |||||||||
 I | 13 (72.2) | 3 (16.7) | 2 (11.1) | 13 (72.2) | 3 (16.7) | 2 (11.1) | 14 (77.8) | 4 (22.2) | 0 (0.0) |
 IIA-IIC | 23 (79.3) | 6 (20.7) | 0 (0.0) | 23 (79.3) | 6 (20.7) | 0 (0.0) | 22 (75.9) | 6 (20.7) | 1 (3.4) |
 IIIA-IIIC | 33 (84.6) | 6 (15.4) | 0 (0.0) | 33 (84.6) | 6 (15.4) | 0 (0.0) | 21 (53.8) | 15 (38.5) | 3 (7.7) |
 IVA-IVB | 12 (100) | 0 (0.0) | 0 (0.0) | 12 (100) | 0 (0.0) | 0 (0.0) | 5 (41.7) | 7 (58.3) | 0 (0.0) |
χ 2, P | 11.682, 0.069 | 11.682, 0.069 | 10.771, 0.096 |