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Table 4 Correlation between changes in levels of clinical parameters and histological scores

From: Analysis of association between circulating miR-122 and histopathological features of nonalcoholic fatty liver disease in patients free of hepatocellular carcinoma

  ΔSteatosis ΔBallooning ΔLobular inflammation ΔStage
r P r P r P r P
ΔAge 0.4 0.011 0.3 0.049 0.3 0.055 0.4 0.026
ΔBody mass index 0.3 0.045 0.3 0.045 0.6 <0.001 0.5 0.004
ΔSerum aspartate aminotransferase 0.4 0.018 0.3 0.126 0.6 <0.001 0.6 <0.001
ΔSerum alanine aminotransferase 0.4 0.018 0.3 0.108 0.5 0.001 0.3 0.054
ΔGamma-glutamyl transpeptidase 0.1 0.555 0.3 0.099 0.3 0.043 0.3 0.044
ΔSerum albumin -0.1 0.748 -0.1 0.393 -0.3 0.110 -0.2 0.165
ΔPlatelet count 0.1 0.740 0.0 0.918 -0.2 0.145 -0.1 0.416
ΔFasting plasma glucose 0.0 0.913 0.2 0.390 0.3 0.102 0.3 0.100
ΔUric acid -0.1 0.671 0.1 0.539 0.2 0.374 0.3 0.089
ΔTotal cholesterol 0.1 0.636 0.3 0.096 0.0 0.992 0.1 0.546
ΔTriglycerides 0.2 0.213 0.1 0.530 0.2 0.195 0.4 0.031
ΔHigh-density lipoprotein cholesterol 0.1 0.738 0.1 0.670 -0.3 0.056 -0.2 0.218
ΔLow-density lipoprotein cholesterol 0.0 0.942 0.2 0.248 0.0 0.855 0.0 0.849
ΔNon high-density lipoprotein cholesterol 0.1 0.675 0.3 0.109 0.1 0.597 0.1 0.385
ΔFerritin 0.3 0.048 0.3 0.063 0.6 <0.001 0.4 0.007
ΔHyaluronic acid 0.2 0.366 0.4 0.036 0.3 0.075 0.5 0.002
Serum miR-122 ratioa 0.5 0.001 0.2 0.226 0.6 <0.001 0.5 0.002
  1. aSerum miR-122 ratio represented the ratio of serum miR-122 level at second biopsy to that at first biopsy
  2. Changes (Δ) in levels of clinical parameters and histopathological scores were calculated by: value at second biopsy minus value at first biopsy
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BMC Gastroenterology

ISSN: 1471-230X

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