Table 7 Suggested therapies requested by the gastroenterologist after their visit
From: Chronic constipation diagnosis and treatment evaluation: the “CHRO.CO.DI.T.E.” study
THERAPIES | 878 pts.(%) | IBS-C (%) | FC (%) | NRC (%) | p-value1 |
|---|---|---|---|---|---|
Life style recommendations | 722 (82.2) | 84.7 | 81.8 | 74.1 | ns |
Dietary suggestions | 749 (85.3) | 85.5 | 85.8 | 79.6 | ns |
Fibre supplements | 489 (55.7) | 60.7 | 53.2 | 55.6 | ns |
Herbal remedies | 46 (5.2) | 6.2 | 4.9 | 3.7 | ns |
Probiotics | 318 (36.2) | 40.4 | 33.5 | 42.6 | ns |
Lactulose/lactitole | 58 (6.6) | 4.7 | 7.8 | 3.7 | ns |
Macrogol | 609 (69.4) | 71.6 | 70.9 | 42.6 # | <0.0001 |
Saline laxatives | 31 (3.5) | 4.0 | 3.5 | 1.9 | ns |
Stimulant laxatives | 55 (6.3) | 6.2 | 6.7 | 1.9 | ns |
Softening laxatives | 46 (5.2) | 5.1 | 5.7 | 1.9 | ns |
Prucalopride | 126 (14.4) | 13.1 | 15.7 | 7.4 | ns |
Suppositories/micro-enemas | 198 (22.6) | 23.6 | 21.3 | 29.6 | ns |
Enemas | 238 (27.1) | 29.5 | 26.6 | 20.4 | ns |
Antispasmodics | 146 (16.6) | 27.6 * ** | 11.7 | 11.1 | <0.0001 |
Anti-bloating agents | 191 (21.8) | 29.1 ^ | 18.6 | 16.7 | <0.005 |
Intestinal antibiotics | 55 (6.3) | 7.3 | 5.5 | 9.3 | ns |
Anxiolytics | 108 (12.3) | 14.6 | 11.5 | 9.3 | ns |
Antidepressants | 60 (6.8) | 8.0 | 6.0 | 9.3 | ns |
Psychotherapy | 35 (4.0) | 6.9 § | 2.7 | 1.9 | <0.05 |
Pelvic floor rehabilitation | 169 (19.3) | 14.6 | 22.2 ° | 13.0 | <0.05 |
Sacral neurostimulation | 3 (0.3) | // | 0.4 | 1.9 | ns |
Anorectal surgery | 20 (2.3) | 1.5 | 2.7 | 1.9 | ns |
Colectomy | 1 (0.1) | // | // | 1.9 | ns |
Other | 18 (2.1) | 2.2 | 2.2 | // | ns |