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Table 2 Irritable bowel syndrome-like symptoms and symptoms of anxiety/depression in patients with ulcerative colitis versus control subjects

From: Patients with longstanding ulcerative colitis in remission do not have more irritable bowel syndrome-like symptoms than controls

 

Ulcerative colitis in remission (n = 55)

Controls (n = 33)

p-value

Median GSRS-IBS scores

 Total score

6.0

10.5

0.062

 Abdominal pain

0.5

0.5

0.57

 Bloating

1.0

1.0

0.19

 Diarrhoea

0.5

0.5

0.38

 Constipation

0.0

0.5

0.048*

 Satiety

0.0

0.0

0.14

Median HADS scores

 Anxiety

4.0

4.0

0.52

 Depression

2.0

2.0

0.99

  1. *Statistically significant
  2. For the specific IBS symptoms the table presents the total score for each cluster divided by number of items for each cluster
  3. Ulcerative colitis in remission was defined by steroid-free clinical remission, a Mayo Score ≤ 1 on endoscopy, a fecal calprotectin ≤ 200 μg/g and no significant active inflammation on colon biopsies.
  4. GSRS-IBS Gastrointestinal symptoms rating scale for irritable bowel syndrome, HADS Hospital anxiety and depression scale