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Table 1 Comparison of HCV+ liver transplant recipients, donors and outcomes in transplantations from HCV+ and HCV-donors

From: Long-term outcomes of liver transplantation in patients with hepatitis C infection are not affected by HCV positivity of a donor

  HCV+ donor HCV- donor P
N 1930 31,738  
Recipients:
 Age, years 55.1 ± 7.2 53.9 ± 7.7 <0.0001
 Male gender 1448 (75.0%) 23,508 (74.1%) 0.35
 Race/ethnicity: Caucasian 1346 (69.7%) 22,575 (71.1%) 0.19
 Race/ethnicity: African-American 267 (13.8%) 3249 (10.2%) <0.0001
 Race/ethnicity: Hispanic 254 (13.2%) 4664 (14.7%) 0.06
 Co-infected with HBV (HBV sAg+) 51 (2.7%) 959 (3.1%) 0.32
 Pre-transplant history of type 2 diabetes 236 (13.3%) 3335 (11.7%) 0.0441
 Liver cancer 544 (28.2%) 7414 (23.4%) <0.0001
 Liver re-transplant 3 (0.2%) 6 (0.0%) 0.0004
 MELD score 18.2 ± 8.3 20.3 ± 9.7 <0.0001
 MELD score excl. liver cancer 19.9 ± 8.3 22.4 ± 9.5 <0.0001
Donors:
 Age, years 42.0 ± 11.8 39.6 ± 16.4 <0.0001
 Male gender 1196 (62.0%) 19,513 (61.5%) 0.67
 Non-heart-beating 31 (1.6%) 1138 (3.6%) <0.0001
 History of diabetes 167 (8.7%) 2491 (7.9%) 0.19
 History of cancer 39 (2.0%) 834 (2.6%) 0.11
 History of high risk behavior 808 (42.4%) 2044 (6.5%) <0.0001
 Heterotopic transplant 2 (0.1%) 35 (0.1%) 0.95
Outcomes:
 Acute rejection episodes before discharge 36 (2.4%) 809 (4.1%) 0.0020
 Discharged alive 1842 (95.4%) 29,808 (93.9%) 0.0063
 Length of inpatient stay, days 15.7 ± 20.3 16.4 ± 21.9 0.0013
 Mortality: 1 year 242 (12.5%) 4467 (14.1%) 0.059
 Mortality: 3 years 399 (24.2%) 7190 (24.8%) 0.58
 Mortality: 5 years 424 (33.0%) 8028 (32.5%) 0.68
 Mortality: 10 years 281 (47.5%) 7019 (48.6%) 0.59
 Graft failure: 1 year 38 (2.2%) 782 (2.8%) 0.15
 Graft failure: 3 years 63 (4.8%) 1375 (5.9%) 0.09
 Graft failure: 5 years 70 (7.5%) 1465 (8.1%) 0.56
 Graft failure: 10 years 50 (13.9%) 1160 (13.5%) 0.86