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Table 1 Comparison of HCV+ liver transplant recipients, donors and outcomes in transplantations from HCV+ and HCV-donors

From: Long-term outcomes of liver transplantation in patients with hepatitis C infection are not affected by HCV positivity of a donor

 

HCV+ donor

HCV- donor

P

N

1930

31,738

 

Recipients:

 Age, years

55.1 ± 7.2

53.9 ± 7.7

<0.0001

 Male gender

1448 (75.0%)

23,508 (74.1%)

0.35

 Race/ethnicity: Caucasian

1346 (69.7%)

22,575 (71.1%)

0.19

 Race/ethnicity: African-American

267 (13.8%)

3249 (10.2%)

<0.0001

 Race/ethnicity: Hispanic

254 (13.2%)

4664 (14.7%)

0.06

 Co-infected with HBV (HBV sAg+)

51 (2.7%)

959 (3.1%)

0.32

 Pre-transplant history of type 2 diabetes

236 (13.3%)

3335 (11.7%)

0.0441

 Liver cancer

544 (28.2%)

7414 (23.4%)

<0.0001

 Liver re-transplant

3 (0.2%)

6 (0.0%)

0.0004

 MELD score

18.2 ± 8.3

20.3 ± 9.7

<0.0001

 MELD score excl. liver cancer

19.9 ± 8.3

22.4 ± 9.5

<0.0001

Donors:

 Age, years

42.0 ± 11.8

39.6 ± 16.4

<0.0001

 Male gender

1196 (62.0%)

19,513 (61.5%)

0.67

 Non-heart-beating

31 (1.6%)

1138 (3.6%)

<0.0001

 History of diabetes

167 (8.7%)

2491 (7.9%)

0.19

 History of cancer

39 (2.0%)

834 (2.6%)

0.11

 History of high risk behavior

808 (42.4%)

2044 (6.5%)

<0.0001

 Heterotopic transplant

2 (0.1%)

35 (0.1%)

0.95

Outcomes:

 Acute rejection episodes before discharge

36 (2.4%)

809 (4.1%)

0.0020

 Discharged alive

1842 (95.4%)

29,808 (93.9%)

0.0063

 Length of inpatient stay, days

15.7 ± 20.3

16.4 ± 21.9

0.0013

 Mortality: 1 year

242 (12.5%)

4467 (14.1%)

0.059

 Mortality: 3 years

399 (24.2%)

7190 (24.8%)

0.58

 Mortality: 5 years

424 (33.0%)

8028 (32.5%)

0.68

 Mortality: 10 years

281 (47.5%)

7019 (48.6%)

0.59

 Graft failure: 1 year

38 (2.2%)

782 (2.8%)

0.15

 Graft failure: 3 years

63 (4.8%)

1375 (5.9%)

0.09

 Graft failure: 5 years

70 (7.5%)

1465 (8.1%)

0.56

 Graft failure: 10 years

50 (13.9%)

1160 (13.5%)

0.86