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Table 2 Comparison of High-resolution Manometry-Multichannel Impedance Parameters in subject groups for liquid and viscous swallows (including failed, weak and fragment swallows)

From: Motility characteristics in the transition zone in Gastroesophageal Reflux Disease (GORD) patients

 

RE

NERD

HO

FH

HV

P values

Liquid swallows

IRP (mmHg)

10.3 (14.4–19.10)

11.50 (6.70–14.60)

11.23 (8.65–14.08)

14.30 (12.13–17.90)

14.15 (11.10–20.52)

0.000

DCI (mmHg · s · cm)

988 (510–1532)

927 (587–1651)

918 (525–1465)

1112 (644–1548)

1240 (933–1744)

0.000

DL (s)

6.4 (5.80–7.10)

6.20 (5.60–7.13)

6.10 (5.50–6.65)

6.60 (6.00–7.30)

6.60 (6.00–7.10)

0.000

TZ delay (s)

1.30 (1.80–2.30)

1.60 (1.10–2.00)

1.70 (1.30–2.45)

1.80 (1.30–2.50)

1.50 (1.25–2.10)

0.142

TZ distance (cm)

2.30 (2.50–4.10)

2.20 (2.60–3.08)

2.95 (2.37–4.45)

3.20 (2.40–5.20)

2.50 (2.20–3.60)

0.140

viscous swallows

IRP (mmHg)

11.90 (8.38–17.00)

9.40 (6.90–12.80)

9.85 (7.28–15.45)

12.80 (9.60–15.00)

12.45 (8.70–18.23)

0.000

DCI (mmHg · s · cm)

720 (184–1413)

766 (426–1525)

651 (210–1484)

927 (333–1565)

1104 (788–1542)

0.000

DL (s)

7.00 (6.30–7.70)

7.00 (5.80–8.35)

6.70 (5.90–7.60)

7.30 (6.60–8.40)

7.40 (6.80–8.10)

0.000

TZ delay (s)

1.45 (2.00–2.70)

2.00 (1.40–2.68)

1.90 (1.40–2.60)

2.00 (1.40–2.63)

2.00 (1.50–2.50)

0.922

TZ distance (cm)

2.80 (2.50–5.75)

4.40 (2.63–6.13)

3.00 (2.25–4.58)

3.20 (2.40–5.85)

3.15 (2.53–4.68)

0.580

  1. RE reflux oesophagitis, NERD non-erosive reflux disease, HO hypertensive oesophagus, FH functional heartburn, HV healthy volunteer, IRP integrated relaxation pressure, DCI distal contractile integral, DL distal latency, TZ transitional zone
  2. Data are presented as median (interquartile range)