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Fig. 5 | BMC Gastroenterology

Fig. 5

From: Soluble ST2 is a sensitive clinical marker of ulcerative colitis evolution

Fig. 5

Immunolocalization of ST2 in colonic tissue from responder and non-responder patients during baseline and 6-month follow-up. a Total ST2 immunoreactivity was restricted to the cellular infiltrate in the lamina propria at 6 months in responder patients (right), while in patients showing reactivation, total ST2 was increased in inflamed mucosa, also confined to the cellular infiltrate (left); baseline examination revealed extensive immune cell infiltration of the intestinal mucosa and damaged tissue with loss of architecture. b Total ST2 immunoreactivity at 6 months expressed as arbitrary units (A.U.) and normalized to baseline levels in responders and non-responders (n = 4 in each group) was higher in the non-responders. Hoechst 33342/ ST2 (blue/green) (60X)

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