Table 1 Characteristics of included cases of malignant serous cystic neoplasms of the pancreas
From: Malignant pancreatic serous cystic neoplasms: systematic review with a new case
Author | Year | Age | Sex | Signs or symptoms | Location | Tumor diameter (cm) | Gross morphologic patten | Distant metastatic sites | Synchronous/Metachronousa | Local invasion sites | Surgical therapy | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
George et al | 1989 | 70 | M | Hemorrhage from gastric varices | body and tail | 11 | Micorocystic | Liver | Synchronous | Stomach, spleen, splenic vein | DP | Death during operation due to hemorrhage |
Friedman et al. | 1990 | 74 | F | Right flank pain, weight loss, palpable mass | head | 19 | Macrocystic | Liver, lung, bone, adrenal glands | Synchronous | None | None | Death due to advanced neoplasm |
Kamei et al. | 1991 | 72 | F | Jaundice | Multifocal origin (head, body,tail) | 10 | Microcystic | Neural invasion | TP | NA | ||
Okada et al. | 1991 | 63 | F | Abdominal pain | body and tail | 12 | Microcystic | Liver | Metachronous (4 years) | None | DP | Alive 5 years after initial operation |
Yoshimi et al. | 1992 | 63 | F | Epigastric pain, palpable mass | body and tail | 12 | Microcystic | Liver | Metachronous (3 years) | None | DP | Alive 6 years after initial operation |
Ohta et al. | 1993 | 64 | M | Unrelated incidental detection of the tumor on abdominal CT | body | 2.5 | Microcystic | Perivascular and vascular invasion | Enucleation | Alive 9 months after initial operation | ||
Widmaier et al | 1996 | 71 | M | Elevated liver function tests | head | 4 | Mixed | Peripancreatic fat | PPPD | Alive 1 year later | ||
Ishikawa et al. | 1998 | 63 | F | Abdominal pain | body | 12 | Microcystic | Liver | Metachronous (3 years) | None | DP | NA |
Eriguchi et al. | 1998 | 65 | F | Palpable abdominal mass | body and tail | 16 | Microcystic | Liver | Both (9 years) | None | DP, micorowave coagulo-necrotic therapy | Alive 10 year after initial operation |
Abe et al. | 1998 | 71 | F | Palpable abdominal mass, general fatigue, weight loss | body and tail | 12 | Microcystic | Lymph node, peripancreatic fat | DP, splenectomy | Alive 2 years later | ||
Horvath et al. | 1999 | 81 | F | NA | NA | 6 | NA | Vessel | DP | NA | ||
Wu et al. | 1999 | 57 | F | Unrelated, incidental detection of the tumor on abdominal CT | entire pancreas | 5.5 | Mixed | Liver, peritoneum | Metachronous (10 year) | Stomach | Pancreatectomy, splenectomy, cholecystectomy | Recurrence 10 years after initial tumor resection |
Strobel et al. | 2001 | 56 | F | Recurrent abdominal pain, diarrhea, weight loss | entire pancreas | 14 | Microcystic | Liver | Metachronous (3 years) | None | PPPD | Alive 3 years after initial operation |
Matsumoto et al. | 2004 | 87 | F | no symptom, incidental finding(inguinal hernia op) | body and tail | 12 | Microcystic | Spleen | Synchronous | Spleen, Vessel | DP with colectomy | Uneventful (10 months) |
Schintaku et al. | 2005 | 85 | F | Fatigue, intermittent diarrhea | body and tail | 12 | Microcystic | Spleen | DP, distal gastrectomy | Alive 10 months later | ||
Friebe et al. | 2005 | 80 | F | Abdominal pain, anorexia, weight loss | body and tail | 8 | Microcystic | Spleen | DP, splenectomy | Alive 1 year later | ||
Gupta et al. | 2008 | 42 | F | Abdominal pain, palpable abdominal mass, diarrhea, weight loss | body and tail | 10 | Macrocystic | peripancreatic fat. | DP, splenectomy | Alive 2 years later | ||
Franko et al. | 2008 | 68 | F | Flank pain, weight loss, anemia, duodenal bleeding | head | 5 | Microcystic | Liver | Metachronous (3 years) | Splenoportal vein, duodenum | Inoperable | Death due to advanced neoplasm, 45 months later |
King et al. | 2009 | 70 | M | Abdominal pain, hematemesis | head | 9 | Microcystic | Duodenum | PPPD | Alive 7 years later | ||
Vadala et al. | 2010 | 74 | M | NA | head | NA | NA | Portal vein | PD, portal vein thrombectomy | NA | ||
Bano et al. | 2011 | 62 | M | Abdominal pain, vomiting, weight loss, jaundice | head | 7 | Microcystic | Liver | Metachronous (1 year) | Duodenum | PD, microwave coagulo-necrotic therapy | Alive 1 year later |
Cho et al. | 2011 | 64 | F | Dizziness, hematochezia | tail | 12 | Microcystic | Colon, spleen invasion | DP, segmental resection of the colon, splenectomy | NA | ||
Bramis et al. | 2012 | 86 | F | Abdominal pain | body | 17 | Microcystic | Liver | Synchronous | Stomach | Inoperable, Biopsies taken | Died 1 month later due to unrelated other medical problem |
Wasel BA et al. | 2013 | 68 | F | Incidental finding | tail | 12 | Microcystic | Liver, retroperitoneum | Inoperable, neo-adjuvant chemotherapy | Alive 1 year later | ||
Rathore MU et al. | 2013 | 60 | F | Upper abdominal pain | body | 9 | Microcystic | Vessels | Partial pancreatectomy and splenectomy | Death 3rd post operative day due to thromboembolism | ||
Kainuma O et al. | 2015 | 69 | M | Upper abdominal discomfort | body | 6 | Solid variant | Liver | Synchronous | None | Distal pancreatectomy(initial diagnossi) + Liver metastatectomy(27 months later) | Alive 30 months later |
Present case | 2015 | 52 | F | Palpable mass | head | 9 | Microcystic | Liver | Metachronous (5 years) | None | PD | Alive 6.5 years later |