Age | Sex | IBD | HBeAg | Highest ALT | Bilirubin at time of highest ALT | Albumin at time of highest ALT | HBV DNA level at time of altered transaminase | IBD medications | Possible cause of altered transaminase | Use of antiviral prophylaxis at time of altered transaminase |
---|---|---|---|---|---|---|---|---|---|---|
33 | M | CD | -ve | 176 | 17 | 40 | 4.21 log IU/mL | 5ASA | Likely immune clearance phase with hepatitis B e-seroconversion | No |
38 | M | CD | +ve | 146 | 14 | 38 | 7.85log IU/mL | Thiopurines, steroid | Possible hepatitis B reactivation vs azathioprine related liver dysfunction | No |
53 | M | UC | +ve | 2520 | 55 | 32 | 7.07log IU/mL | 5ASA, Steroid | Possible hepatitis B reactivation | No |
46 | M | CD | -ve | 162 | 12 | 38 | 4.02log IU/mL | Thiopurines | Transient liver dysfunction with uncertain cause | No |
32 | F | UC | -ve | 207 | 9 | 41 | 2.44log IU/mL | 5ASA | Likely related to hyperemesis gravidum | No |
36 | F | CD | +ve | 592 | 11 | 26 | Undetectable | Thiopurines, Steroid, Biologics, | Possibly related to TPN; unlikely related to hepatitis B reactivation | Yes |